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| Clinical data | |
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| Other names | 4-Isopropoxy-3,5-dimethoxyphenethylamine |
| Routes of administration | Oral[1] |
| Drug class | Serotonergic psychedelic;Hallucinogen |
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| Pharmacokinetic data | |
| Duration of action | 10–16 hours[1] |
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| Chemical and physical data | |
| Formula | C13H21NO3 |
| Molar mass | 239.315 g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 163 to 164 °C (325 to 327 °F) (hydrochloride) |
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Isoproscaline or4-isopropoxy-3,5-dimethoxyphenethylamine is ananalogue ofmescaline.[1] It is closely related toproscaline and was first synthesized byDavid E. Nichols and colleagues.[2] It producespsychedelic effects.
Little is known about thepsychopharmacological effects of isoproscaline. In his bookPiHKAL,Alexander Shulgin lists a psychedelic dose as being 40–80 mg, with effects lasting 10–16 hours.[1]
The mechanism that produces the hallucinogenic and entheogenic effects of isoproscaline is most likely to result from action as a5-HT2Aserotonin receptoragonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines andphenethylamines.
Isoproscaline is in a class of compounds commonly known asphenethylamines, and the full chemical name is 2-(4-isopropoxy-3,5-dimethoxyphenyl)ethanamine.
Isoproscaline is unscheduled in theUnited States; however, because of its close similarity in structure and effects tomescaline, possession and sale of isoproscaline may be subject to prosecution under theFederal Analog Act.
In the UK, its highly likely that this compound would be covered by the "phenylethylamine amendment" to the misuse of drugs act likely rendering it a Class A controlled drug.
