Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Isopropamide

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Isopropamide
Clinical data
MedlinePlusa694006
Routes of
administration
Oral
ATC code
Legal status
Legal status
Identifiers
  • 4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.028.470Edit this at Wikidata
Chemical and physical data
FormulaC23H33N2O+
Molar mass353.530 g·mol−1
3D model (JSmol)
  • O=C(N)C(c1ccccc1)(c2ccccc2)CC[N+](C(C)C)(C(C)C)C
  • InChI=1S/C23H32N2O/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26)/p+1 checkY
  • Key:JTPUMZTWMWIVPA-UHFFFAOYSA-O checkY
 ☒NcheckY (what is this?)  (verify)

Isopropamide (R79) is a long-actinganticholinergicdrug. It is used in the treatment ofpeptic ulcers and othergastrointestinal disorders involving hyperacidity (gastrointestinalacidosis) and hypermotility.[citation needed] Chemically, it contains aquaternary ammonium group. It is most often provided as aniodide salt, but is also available as a bromide or chloride salt. It was discovered atJanssen Pharmaceutica in 1954.[citation needed]

References

[edit]

Further reading

[edit]
  • Seeherman R (October 1957). "Isopropamide iodide: a long-acting anticholinergic".Delaware Medical Journal.29 (10):265–9.PMID 13473394.
  • Boss Jr EG, Buchanan GC (November 1957). "Effect of isopropamide iodide on basal gastric secretion in the human".Gastroenterology.33 (5):730–6.doi:10.1016/S0016-5085(19)35625-2.PMID 13480414.
Drugs for
functional
bowel
disorders
Antimuscarinics
Tertiary
amino group
Quaternary
ammonium

compounds
Phosphodiesterase
inhibitors
Acting on
serotonin receptors
Other
Belladonna
and derivatives
(antimuscarinics)
Propulsives
mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(andprodrugs)
Stub icon

Thisdrug article relating to thegastrointestinal system is astub. You can help Wikipedia byadding missing information.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Isopropamide&oldid=1332188839"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2026 Movatter.jp