I-75 highlighted in red | ||||
| Route information | ||||
| Maintained byFDOT | ||||
| Length | 470.808 mi[1] (757.692 km) | |||
| Existed | 1956–present | |||
| NHS | Entire route | |||
| Major junctions | ||||
| South end | ||||
| Major intersections | ||||
| North end | ||||
| Location | ||||
| Country | United States | |||
| State | Florida | |||
| Counties | Miami-Dade,Broward,Collier,Lee,Charlotte,DeSoto,Sarasota,Manatee,Hillsborough,Pasco,Hernando,Sumter,Marion,Alachua,Columbia,Suwannee,Hamilton | |||
| Highway system | ||||
| ||||
| ||||
Interstate 75 (I-75) is a part of theInterstate Highway System that runs from theHialeah–Miami Lakes border, a few miles northwest ofMiami, toSault Ste. Marie in theUpper Peninsula of Michigan. I-75 begins its national northward journey near Miami, running along the western parts of theMiami metropolitan area before traveling westward acrossAlligator Alley (also known asEverglades Parkway[2]), resuming its northward direction inNaples, running along Florida'sGulf Coast, and passing the cities ofFort Myers,Punta Gorda,Venice, andSarasota. The freeway passes through theTampa Bay area before turning inward towardOcala,Gainesville, andLake City before leaving the state and enteringGeorgia. I-75 runs for 471 miles (758 km) in Florida, making it the longest Interstate in the state and also the longest in any state east of theMississippi River. The Interstate's speed limit is 70 mph (110 km/h) for its entire length in Florida.
The portion of I-75 from Tampa northward was a part of the original 1955 Interstate Highway plans, with I-75's southern terminus atI-4's current western terminus. Planning to extend the Interstate south to Miami began in 1968 after massive growth inSouthwest Florida, which resulted in I-75 being realigned to travel on the eastern fringes of the Tampa Bay area, and the last portion of the highway was opened in 1993.
ForFlorida Department of Transportation (FDOT) inventory purposes, it is designated as State Road 93 (SR 93) for most of its length in Florida (with exception to the Tampa Bay area, where SR 93 followsI-275, whileSR 93A travels with I-75 in the latter's bypass of the area).

I-75 begins its northward journey at aninterchange withSR 826 (Palmetto Expressway) andSR 924 (Gratigny Parkway) on theHialeah–Miami Lakes border, near Miami.[3]
As it curves around the border of Miami Lakes, I-75 serves some of the western fringes ofSouth Florida as an eight-lane highway. After an exit withSR 860, I-75 has an interchange with theHomestead Extension of Florida's Turnpike before crossing intoBroward County. There, it continues through the western suburbs ofPembroke Pines,Weston,Miramar,Davie, andSouthwest Ranches.
At the junction ofSR 869 (Sawgrass Expressway) andI-595, I-75 (while maintaining its south–north status) enters a west–east trajectory as it crosses theEverglades by way of Alligator Alley, a toll road that runs from the Collier Boulevard (exit 101) toll plaza to theU.S. Highway 27 (US 27) toll plaza (exit 23). It was originally constructed as a two-lane highway before it was converted to a four-lane highway meeting Interstate Highway standards. At this point, I-75 loses a lane in each direction, heading west, losing another lane west of the US 27 interchange.

The Alligator Alley section of I-75 runs due east–west between exit 19 inSunrise and exit 101 just east of Naples and is one of only two sections along the Interstate's entirety that is tolled (the other is theMackinac Bridge in northern Michigan). Tolls are $3.75 for a two-axle vehicle as of July 1, 2023, and are collected in both directions.[4] The highway's toll plazas accept both cash and transponders in theSunPass network and are located at either entrance to Alligator Alley. The toll facilities along Alligator Alley and toll revenue collected from them are overseen byFlorida's Turnpike Enterprise (FTE). There are two interchanges along the 75-mile (121 km) tolled portion of Alligator Alley in addition to three rest areas and a number of scenic outlook points as the highway crosses the Everglades. I-75 entersCollier County along Alligator Alley just west of the Snake Road exit (exit 49) and passes through theBig Cypress National Preserve between the Collier County border andSR 29 (exit 80). Several small bridges along Alligator Alley allow wildlife to pass safely under the freeway, especially along theFlorida Panther National Wildlife Refuge east of SR 29. Extensive fencing also prevents wildlife from interfering with traffic.[5]
As it approachesNaples atCounty Road 951 (CR 951; exit 101), Alligator Alley ends. The Interstate is toll-free for the rest of its length in Florida and makes a sharp turn north, resuming its north–south trajectory, and as it parallels Florida's west coast, it becomes six lanes. As it continues north, I-75 passes nearBonita Springs,Fort Myers,Punta Gorda,Port Charlotte,Venice,Sarasota, andBradenton before reaching theTampa Bay area metropolis consisting ofTampa andSt. Petersburg.

North ofEllenton,I-275 splits from I-75 to serve St. Petersburg andPinellas County via theSunshine Skyway Bridge and Tampa via theHoward Frankland Bridge. I-75 parallels the eastern shore of Tampa Bay as a bypass route of the Tampa Bay area, as it passes by the communities ofBrandon,Temple Terrace, andNew Tampa. Two expressways accessDowntown Tampa from I-75: theLee Roy Selmon Expressway (SR 618) andI-4. Within the Tampa Bay metropolitan area, many interchanges are far more complex than merediamond,cloverleaf, or evensingle-point urban interchanges. Aside from the largeturbine interchange with I-4 (exit 261), there are interchanges withSR 582 (Fowler Avenue; exit 265) andSR 579 (Fletcher Avenue/Morris Bridge Road; exit 266) that contain both loops and flyovers. A flyover ramp was built from southboundSR 581 (Bruce B. Downs Boulevard; exit 270) to southbound I-75.[6]

At theHillsborough–Pasco county line (south ofSR 56 [exit 275]), I-275 rejoins I-75 (at exit 274, southbound only) and I-75 changes into a southwest–northeast trajectory as it passes through Pasco,Hernando, andSumter counties where it runs through parts of theWithlacoochee State Forest on its way to the junction withFlorida's Turnpike (exit 328, accessible from southbound I-75 only [although northbound travelers can access the Turnpike from I-75's exit 329 and followSR 44 to the Turnpike's exit 304]). Widened median segments exist in northern Pasco, Hernando, and Sumter counties north ofCR 476B (exit 309). Some of these median segments are actually considered part of the Withlacoochee State Forest itself. TheWithlacoochee State Trail runs beneath I-75 betweenUS 98/SR 50 (exit 301) and the Hernando–Sumter county line, where it also crosses over theWithlacoochee River. All of I-75 from the Georgia border to Tampa is three lanes in each direction, unless closed for construction. This is to accommodate for the immense number of tourists and vacationers that come to Florida.
After Florida's Turnpike, I-75 changes into a general southeast–northwest trajectory, which is sustained to the Georgia state line and beyond. I-75 passes beneath theCross Florida Greenway, which contains a land bridge built across the highway in 2001 between exits 341 and 350,[7] before entering the city ofOcala, and passing by the cities ofGainesville andLake City and crossesI-10 at an interchange before entering the state of Georgia, nearValdosta.


I-75 runs closest toUS 41 except between Tampa andHigh Springs. It runs closer toUS 301 betweenEllenton andTemple Terrace, and again fromDade City toSparr. FromBelleview to Lake City, it runs closest toUS 441.[8]

Original plans for I-75 called for its southern terminus to be inTampa, where it would terminate atI-4 (at the current interchange between I-4 and I-275, with I-4, which was completed in the Tampa Bay area by 1962, continuing west along what is now I-275 over theHoward Frankland Bridge intoSt. Petersburg).[citation needed] Plans for I-75 from Tampa toSault Ste. Marie, Michigan, were authorized as part of theFederal-Aid Highway Act of 1956, signed into law by PresidentDwight D. Eisenhower, which created theInterstate Highway System.[citation needed]
Construction of the original route from the Georgia border to Tampa viaGainesville andOcala lasted through most of the 1960s. The first segment of I-75 to open in Florida was from the Georgia border to SR 6 just south ofJennings, which opened in 1963. It would reachUS 90 in Lake City later that year. By mid-1964, I-75 opened from Lake City to the newly completedFlorida's Turnpike (known then as the Sunshine State Parkway) inWildwood. Segments of the original route that are now part of I-275 near Tampa would begin opening in 1966, and construction of the full route would be completed by 1969.[citation needed]
Due to major growth inSouthwest Florida (particularly Fort Myers and Naples), it was becoming clear that this part of the state would soon need a freeway. Florida's state government first proposed to build a West Coast Turnpike in 1964 from the Tampa Bay area south to Naples.[9] Plans for the West Coast Turnpike (which would have been tolled) were canceled in 1968, when it was announced that US Secretary of TransportationAlan S. Boyd had approved an extension of I-75 south to Naples and then east to Miami. The federal government would pay for 90 percent of the extension using funds allocated by theFederal-Aid Highway Act of 1968, which was signed into law by PresidentLyndon B. Johnson.[10][11]
In preparation for the extension, I-75's designation was extended along the preexisting route of I-4 over theHoward Frankland Bridge into St. Petersburg by the end of 1969 (I-4's designation would be truncated to its current terminus at this time). From St. Petersburg, I-75 was proposed to continue south over theSunshine Skyway Bridge and continue south along a new freeway roughly parallel to theTamiami Trail (US 41) along the lower Gulf Coast to Naples.
As the extension was planned in 1968, plans were also made for a freeway bypassing Tampa Bay to the east. The bypass was initially planned to be designatedInterstate 75E (I-75E), and was to split from I-75 nearWesley Chapel and rejoin it just north ofEllenton. However, in 1972, it was determined that maintaining the main route of I-75 through Downtown Tampa would eventually require major improvements to the existing infrastructure to handle through traffic. Additionally, neither the 1954 nor 1971 spans of the original Sunshine Skyway Bridge were up toInterstate Highway standards as they both lacked shoulders.[12] As a result, it was decided that I-75 would be re-routed and instead follow the bypass route. FDOT could have renumbered I-75E into what could have possibly beenInterstate 75W (I-75W), but, due to a 1973-basedAmerican Association of State Highway and Transportation Officials (AASHTO) rule indicating that suffixed routes were to be renumbered to reduce motorist confusion, the option of renumbering I-75E into I-75W was scrapped, with the I-75E designation instead being renumbered to what is known today as I-275, and both the I-75 and I-275 designations were swapped into their current configuration in 1973. I-75 reached as far south as 38th Avenue North in St. Petersburg when the designations were switched. Despite the designation switch, both freeways' hidden designations still reflect the originally planned routing, with I-75's SR 93 designation following I-275, and the current route of I-75 on the bypass being designated SR 93A.[13] Construction on the bypass segment of I-75 began in 1979.[citation needed]
The initially favored proposal for I-75 to reach Miami from Naples was to have I-75 run along the Tamiami Trail (US 41) across the Everglades to just east of theSR 826 (Palmetto Expressway) where it would continue alongSR 836 (Dolphin Expressway) and terminate atI-95 andI-395 inDowntown Miami.[14] However, in 1973, planners made the decision to shift I-75's proposed route to cross the Everglades along Alligator Alley over environmental concerns related to upgrading the Tamiami Trail, which runs along the northern border ofEverglades National Park. Additionally, Alligator Alley itself needed upgrading, as the then-narrowtoll road was dangerous to both motorists and wildlife (most notably theFlorida panther) alike, and the Dolphin Expressway, with its left exits and narrow lanes, was not being built toInterstate Highway standards, with the costs to upgrade it being too expensive. By using this route, I-75 would run along the alley to the proposed Port Everglades Expressway, where it would turn south along a new freeway through the western suburbs ofWeston andPembroke Pines to Miami. It was still planned to continue east to I-95, but, due to local opposition, I-75 was not built past its current terminus at SR 826 (Palmetto Expressway) inHialeah. With this new route, the Port Everglades Expressway was then planned to be built as an Interstate Highway designatedI-595 to provide an Interstate connection between I-75 and I-95.
The first piece of the south extension of I-75 to open was a short segment just east of Fort Myers from SR 78 south to Corkscrew Road in 1979. This piece would extend north to Tucker's Grade just south of Punta Gorda in early 1980 and south to Immokalee Road in North Naples by 1981. Also in 1981, the segment from US 301 inManatee County south to River Road near Venice opened, which would be completed south to the southern segment inPunta Gorda later that year. It would reach Alligator Alley in Naples by 1984. The route from Tampa to Naples would be complete by 1986 as segments of the Tampa bypass were opened from 1982 to 1986. In the Miami area, I-75 was opened from US 27 to its terminus at the Palmetto Expressway in 1986.[citation needed]
The Alligator Alley segment of I-75 extends from atoll plaza just east ofNaples to an interchange with I-595 and the Sawgrass Expressway (SR 869) in Sunrise just west ofFort Lauderdale. The highway previously existed as a two-lane tollway connecting the two coasts of Florida. Initially known as the Everglades Parkway (SR 84), it opened for traffic on February 11, 1968, after four years of construction. Built by H. L. Mills Construction Company, it had been called the most controversial roadway ever built in Florida during its initial construction.[15] The name "Alligator Alley" was given by theAmerican Automobile Association (AAA) while it was being planned as they believed it would be useless to cars and merely an "alley foralligators". As alligators frequent the waterways beside the road, and occasionally the roadway itself, the nickname developed a literal meaning. The state moved to officially adopt the "Alligator Alley" name in August 1966.[15]
As a two-lane road, Alligator Alley suffered from poor construction and environmental planning. It was also notorious for high-speed accidents, including both head-on collisions and collisions with wildlife. The need to improve the road was one of the factors considered in the decision to reroute I-75 onto Alligator Alley, which was rebuilt as a four-lane Interstate Highway between 1986 and 1992. Many bridges and culverts designed to let water and wildlife pass underneath the roadway and permit the natural flow of the Everglades' waters were built as part of the upgrade.[16] This helped to reduce theenvironmental impact of the highway, especially upon the severelyendangeredFlorida panther. The completion of the converted Alligator Alley was the final link of the I-75 extension. The segment was signed I-75 on November 25, 1992, completing the highway from Miami toSault Ste. Marie, Michigan.[17]
In 1999, the East Toll Plaza was converted to only serving northbound traffic, while the West toll plaza was converted to serving only southbound traffic. This was done to reduce congestion.[citation needed]
In January 2000, the west end toll plaza of Alligator Alley was dedicated to the memory of Edward J. Beck, a toll collector who was murdered on the job on January 30, 1974.[18]
FDOT transitioned existing interchange exit numbers on all Interstate Highways from sequential exits to mileage-based exits in January 2002.[19]
In April 2008, FDOT proposed a 72-mile (116 km) section of road to be leased to private operators. The additional revenue the state would receive was one of primary motives toprivatize this section of Alligator Alley.[20] However, the motion failed in May 2009 when no bids were received that met the required terms.[21]
In fall 2016, a six-lane widening was completed between Sumter Boulevard and North River Road.[citation needed]
FDOT contracted Prince Contracting in 2015 to construct the state's firstdiverging diamond interchange at theUniversity Parkway (exit 213) interchange.[22] The $74.5-million (equivalent to $93.5 million in 2024[23]) project started construction in August 2015 and completed in September 2017.[24] The interchange handles more than 80,000 vehicles per day and reduced intersection delays by 50 percent.[25]
FDOT implemented express lanes along 28 miles (45 km) of the I-75 and SR 826 (Palmetto Expressway) corridors, from just south of the SR 836 (Dolphin Expressway), inMiami-Dade County, to I-595 inBroward County. The project completed another section of the South Florida managed lanes network for all motorists and improves mobility, relieves congestion, provides additional travel options, and accommodates future growth in the area. The 75 Express Lanes project extends 15 miles (24 km) along I-75 from Northwest 170th Street, in Miami-Dade County, to I-595, in Broward County. Work was completed in four segments to minimize the effects on the public. Construction began in early 2014 and was completed in 2018. The total project cost $481 million (equivalent to $590 million in 2024).[26][23]
In 2015, theCentral Florida Expressway Authority (CFX), FDOT, andFTE announced a $68.5-million (equivalent to $88.3 million in 2024)[23] project to make several improvements to I-75's interchange with SR 44 (exit 329) and the adjoining interchange with Florida's Turnpike (exit 328). This included adding acollector–distributor ramp in each direction along I-75 leading to the interchange northbound, and leading from SR 44 to the southbound Turnpike, as well as widening I-75 to six lanes in each direction leading to the interchange, and adding another access point from the northbound Turnpike to SR 44 (exit 307). The project, which was handled by Middlesex Construction, began construction in September 2016. The new northbound offramp to SR 44 was completed on September 19, 2019, and the new southbound onramps to the Turnpike and I-75 were completed in early November 2019. The project overall was completed in January 2020.[27]
Another diverging diamond interchange withSR 56 (exit 275) was initially proposed in May 2018;[28] construction on the revamped intersection began in February 2019,[29] and it was completed in 2022.[citation needed]
An additional interchange was planned for Overpass Road north ofSR 54, connecting toCR 530.[30][31] The interchange opened to traffic the morning of January 18, 2023.[citation needed]
Another diverging diamond interchange with Northwest 49th Street in Ocala (exit 356) was initially proposed in November 2020. The project, which is projected to cost $147.9 million, is scheduled to begin construction in June 2025.[32]
Several rest area facilities exist along I-75 throughout the state. In addition, there are separate facilities for each direction of the Interstate inHamilton andSuwannee counties, southbound and northbound, respectively, and awelcome center south of the state line. Exit 131 has a single facility accessible from both travel directions on I-75, as well as the intersecting highway. Exit 161 had a rest stop at the interchange's southeast quadrant, but it closed in 2015 because of low usage.[33] Exit 191 also had a rest stop at the interchange's northeast quadrant that closed in the 1990s.[citation needed] Each rest area has restrooms, vending machines, picnic tables, dog walk areas, and nighttime security. The welcome center also has travel information and freeorange juice, the state's officialstate beverage.[34]
Motorist-aidcall boxes were installed starting in 1973, initially from the Georgia line to Lake City,[35] eventually being installed on both outside shoulders of the road every one mile (1.6 km) to allow drivers to indicate the need for gasoline, repair (tire or engine), oremergency services (police, ambulance, or fire). The majority of the call boxes were removed in late 2013 because of the rising maintenance cost and the availability of newer technology.[36]
Intelligent transportation systems (ITS) are used throughout the Interstate. ITS is a fiber optic system of traffic cameras, overhead message signs, microwave vehicle detectors, travel time sensors, road and weather information sensors, and highway advisory radios.[36] FDOT has a data-share agreement withWaze which provides real-time information for the state's5-1-1 service, ITS, and to Waze users.[37]
| County | Location | mi[1] | km | Old exit | New exit | Destinations | Notes | |
|---|---|---|---|---|---|---|---|---|
| Miami-Dade | Miami Lakes–Hialeah line | 0.000 | 0.000 | Continuation east | ||||
| 1 | 1 | Signed as exits 1A (north) and 1B (south) | ||||||
| 1.470 | 2.366 | 2 | 2 | Northwest 138th Street, Hialeah Gardens Boulevard | ||||
| | 4.454 | 7.168 | 3A | 4 | Western terminus of SR 860; Park and Ride on west side of interchange | |||
| Southern terminus of express lanes | ||||||||
| Miami-Dade–Broward county line | Hialeah–Miramar line | 4.923 | 7.923 | 3B | 5 | No northbound exit to Turnpike south or southbound entrance from Turnpike north; exit 39 on Turnpike | ||
| Broward | Miramar | 6.966 | 11.211 | 4 | 7 | To Memorial Hospital Miramar | ||
| Southbound exit and northbound entrance | ||||||||
| Pembroke Pines | 9.204 | 14.812 | 5 | 9 | Signed as exits 9A (east) and 9B (west); to Memorial Hospital West,Pembroke Lakes Mall,C. B. Smith Park,Broward College/FIU at 75,Keiser University - Pembroke Pines | |||
| Southbound exit and northbound entrance | ||||||||
| Pembroke Pines–Davie line | 10.867 | 17.489 | 6 | 11 | To Memorial Hospital Pembroke,Brian Piccolo Park,Broward College - Pines Center | |||
| Davie | Northbound exit and southbound entrance | |||||||
| Davie–Southwest Ranches– Weston tripoint | 13.166 | 21.189 | 7 | 13 | Signed as exits 13A (east) and 13B (west) | |||
| Southbound exit and northbound entrance | ||||||||
| Davie–Weston line | 14.997 | 24.135 | 8 | 15 | To Cleveland Clinic Florida | |||
| Davie–Weston– Sunrise tripoint | 17.379 | 27.969 | 10 | 19 | Western terminus of I-595; southern terminus of SR 869 | |||
| Weston | 21.119 | 33.988 | 11 | 21 | Northbound exit and southbound entrance (exit 22 provides full access) | |||
| 22.064 | 35.509 | 12 | 22 | |||||
| 23.494 | 37.810 | 13 | 23 | UnsignedSR 25; toEverglades Holiday Park | ||||
| | 25[38] | 40 | East Toll Plaza (northbound only) | |||||
| 35.3[38] | 56.8 | Recreational and rest areas | ||||||
| Miccosukee Reservation | 49.428 | 79.547 | 14 | 49 | Access to Miccosukee Service Plaza; to Big Cypress Seminole Reservation,Ah-Tah-Thi-Ki Seminole Indian Museum, and Billie's Swamp Safari | |||
| Collier | | 63.0[38] | 101.4 | Rest area | ||||
| Miles City | 80.048 | 128.825 | 14A | 80 | ||||
| | 100[38] | 160 | West Toll Plaza (southbound only) | |||||
| 101.284 | 163.001 | 15 | 101 | |||||
| 104.552 | 168.260 | -- | 105 | |||||
| 107.134 | 172.415 | 16 | 107 | Future diverging diamond interchange | ||||
| 111.401 | 179.283 | 17 | 111 | |||||
| Lee | Bonita Springs | 115.385 | 185.694 | 18 | 116 | |||
| Estero | 122.748 | 197.544 | 19 | 123 | ToFlorida Gulf Coast University,Coconut Point Mall,Koreshan State Historic Site | |||
| Three Oaks | 127.068 | 204.496 | 20 | 128 | ToHertz Arena andFlorida Gulf Coast University | |||
| | 130.808 | 210.515 | 21 | 131 | Rest area northeast of this interchange; future diverging diamond interchange; toGulf Coast Medical Center | |||
| Fort Myers | 135.426 | 217.947 | 22 | 136 | Diverging diamond interchange; to Lee Memorial Hospital | |||
| 136.985 | 220.456 | 23 | 138 | |||||
| | 138.494 | 222.884 | 24 | 139 | ||||
| 140.416 | 225.978 | 25 | 141 | |||||
| Caloosahatchee River | 140.926– 141.666 | 226.798– 227.989 | Bridge | |||||
| North Fort Myers | 142.777 | 229.777 | 26 | 143 | ||||
| Charlotte | | 157.004 | 252.673 | 27 | 158 | |||
| 158.8[38] | 255.6 | Weigh station | ||||||
| 160.270 | 257.930 | 28 | 161 | |||||
| Solana | 163.611 | 263.306 | 29 | 164 | ToBayfront Health Punta Gorda | |||
| Peace River | 164.304[38]– 165.832 | 264.422– 266.881 | Bridge | |||||
| | 166.395 | 267.787 | 30 | 167 | ||||
| 169.573 | 272.901 | 31 | 170 | |||||
| DeSoto | No major junctions | |||||||
| Sarasota | North Port | 178.559 | 287.363 | 32 | 179 | |||
| 181.505 | 292.104 | 33 | 182 | |||||
| | 190.580 | 306.709 | 34 | 191 | ||||
| 192.821 | 310.315 | 35 | 193 | |||||
| Venice | 195.120 | 314.015 | 35A | 195 | To Sarasota Memorial Hospital - Venice campus | |||
| | 199.319 | 320.773 | 36 | 200 | Southbound exit and northbound entrance; former I-75 south | |||
| 204.884 | 329.729 | 37 | 205 | |||||
| Lake Sarasota | 206.906 | 332.983 | 38 | 207 | ToHCA Florida Sarasota Doctors Hospital, Suncoast Technical College, Marie Selby Botanical Gardens | |||
| Fruitville | 209.622 | 337.354 | 39 | 210 | Future diverging diamond interchange; to Lakewood Ranch Medical Center,Downtown Sarasota Historic District,Mote Aquarium,Nathan Benderson Park | |||
| Sarasota–Manatee county line | Lakewood Ranch | 213.139 | 343.014 | 40 | 213 | ToNew College of Florida,USF Sarasota- Manatee,University Town Center,Ringling Museum, Lakewood Ranch Medical Center | ||
| Manatee | | 216.826 | 348.948 | 41 | 217 | |||
| 220.425 | 354.740 | 42 | 220 | ToManatee Memorial Hospital | ||||
| Manatee River | 223.498[38]– 224.226 | 359.685– 360.857 | Bridge | |||||
| | 224.103 | 360.659 | 43 | 224 | ||||
| 227.874 | 366.728 | 44 | 228 | |||||
| 229.290 | 369.006 | 45 | 229 | |||||
| Hillsborough | Ruskin | 237.2[38] | 381.7 | Rest area | ||||
| Ruskin–Sun City Center line | 240.126 | 386.445 | 46 | 240 | Signed as exits 240A (east) and 240B (west) southbound; to South Bay Hospital | |||
| Gibsonton | 245.966 | 395.844 | 47 | 246 | To St. Joseph Hospital South | |||
| Gibsonton–Riverview line | 250.158 | 402.590 | 48 | 250 | Gibsonton Drive –Gibsonton,Riverview | |||
| Brandon | 253.741 | 408.357 | 49 | 254 | ToBrandon Town Center | |||
| 255.587 | 411.327 | 50 | 256 | Exit 15 on SR 618 | ||||
| 256.559 | 412.892 | 51 | 257 | To HCA Florida Brandon Hospital,Hillsborough Community College | ||||
| Mango | 259.307 | 417.314 | 52 | 260 | Diverging diamond interchange; access to St. Joseph's Hospital, St. Joseph's Children's Hospital, and St. Joseph's Women's Hospital; ToFlorida State Fairgrounds | |||
| 260.729 | 419.603 | 53 | 261 | Exit 9 on I-4 | ||||
| Temple Terrace | 264.803 | 426.159 | 54 | 265 | ToUniversity of South Florida,Museum of Science & Industry (Tampa),Busch Gardens | |||
| Temple Terrace–Tampa line | 265.814 | 427.786 | 55 | 266 | To AdventHealth Tampa and Moffitt Cancer Center | |||
| Tampa | 269.849 | 434.280 | 56 | 270 | To Veterans Hospital | |||
| Pasco | Wesley Chapel | 273.708 | 440.490 | 57 | 274 | Southbound exit and northbound entrance | ||
| 275.200 | 442.891 | 57A | 275 | To AdventHealth Center Ice Sports Complex,Pasco–Hernando State College | ||||
| 277.0[38] | 445.8 | Rest area | ||||||
| 278.670 | 448.476 | 58 | 279 | To BayCare Hospital Wesley Chapel | ||||
| 282 | Overpass Road | Opened January 18, 2023[39] | ||||||
| | 285.295 | 459.138 | 59 | 285 | ||||
| 292.620 | 470.926 | 60 | 293 | |||||
| Hernando | | 300.969 | 484.363 | 61 | 301 | |||
| Sumter | Withlacoochee State Forest | 306.0[38] | 492.5 | Rest area | ||||
| | 307.125 | 494.270 | 62 | 309 | ||||
| 313.036 | 503.783 | 63 | 314 | |||||
| Lake Panasoffkee | 319.468 | 514.134 | 64 | 321 | ||||
| | 326.797 | 525.929 | 65 | 328 | Left southbound exit and right northbound entrance; northern terminus of Turnpike | |||
| 328.004 | 527.871 | 66 | 329 | |||||
| Marion | | 337.1[38] | 542.5 | Weigh station | ||||
| Marion Oaks | 339.357 | 546.142 | 67 | 341 | ||||
| | 344.6[38] | 554.6 | Rest area | |||||
| Ocala | 348.340 | 560.599 | 68 | 350 | ToAdventHealth Ocala, HCA Florida Ocala Hospital,College of Central Florida | |||
| 350.816 | 564.584 | 69 | 352 | |||||
| 352.195 | 566.803 | 70 | 354 | |||||
| 356 | Northwest 49th Street | Proposed diverging diamond interchange; construction slated for 2025 | ||||||
| | 356.478 | 573.696 | 71 | 358 | ||||
| Irvine | 366.723 | 590.183 | 72 | 368 | ||||
| Alachua | | 373.650 | 601.331 | 73 | 374 | |||
| Paynes Prairie Preserve State Park | 381.5[38] | 614.0 | Rest area | |||||
| Gainesville | 382.390 | 615.397 | 74 | 382 | ToUniversity of Florida | |||
| 383.694 | 617.496 | 75 | 384 | ToUF Health Shands Hospital,University of Florida,Florida Museum of Natural History | ||||
| 387.218 | 623.167 | 76 | 387 | To HCA Florida North Florida Hospital,University of Florida,The Oaks Mall | ||||
| | 389.815 | 627.346 | 77 | 390 | ToGainesville Regional Airport,Santa Fe College | |||
| Alachua | 398.854 | 641.893 | 78 | 399 | ||||
| Traxler | 404.225 | 650.537 | 79 | 404 | ||||
| Columbia | | 411.8[38] | 662.7 | Rest area | ||||
| Ellisville | 413.709 | 665.800 | 80 | 414 | ||||
| | 422.632 | 680.160 | 81 | 423 | ||||
| Lake City | 427.351 | 687.755 | 82 | 427 | To HCA Florida Lake City Hospital | |||
| | 434.702 | 699.585 | 83 | 435 | Exit 296 on I-10 | |||
| Suwannee | | 439.386 | 707.123 | 84 | 439 | |||
| Hamilton | | 445.4[38] | 716.8 | Inspection station | ||||
| 448.5[38] | 721.8 | Weigh station | ||||||
| 451.262 | 726.236 | 85 | 451 | |||||
| 460.350 | 740.862 | 86 | 460 | |||||
| Jennings | 466.825 | 751.282 | 87 | 467 | ||||
| | 469.0[38] | 754.8 | Florida Welcome Center (southbound only) | |||||
| 470.808 | 757.692 | Continuation into Georgia | ||||||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
| ||||||||
All exits are unnumbered.
| County | Location | mi | km | Destinations | Notes |
|---|---|---|---|---|---|
| Miami-Dade | Hialeah | Express lanes continue on Palmetto Expressway southbound | |||
| Northwest 138th Street | Access via local lanes to exit 2; southbound exit northbound entrance | ||||
| Miami-Dade–Broward county line | Hialeah–Miramar line | Southbound exit and northbound entrance; exit 39 on Turnpike | |||
| Broward | Miramar | Access via local lanes to exits 9 and 11 | |||
| Davie–Weston line | Griffin Road, Royal Palm Boulevard | Access via local lanes to exits 13 and 15 | |||
| Davie–Weston– Sunrise tripoint | Northbound exit and southbound entrance; access via local lanes to exit 19 | ||||
| Continues as peak-direction I-595 express lanes | |||||
| 1.000 mi = 1.609 km; 1.000 km = 0.621 mi | |||||
InJohn D. MacDonald's novel,The Long Lavender Look, part of his series about fictional detectiveTravis McGee, the story takes place on Alligator Alley and in nearby towns accessible from it.
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