Movatterモバイル変換

[0]ホーム

Jump to content

Integrin alpha D

Edit links

From Wikipedia, the free encyclopedia

(Redirected fromITGAD)

Protein-coding gene in the species Homo sapiens

ITGAD

Identifiers

Aliases

ITGAD, ADB2, CD11D, integrin subunit alpha D

External IDs

OMIM:602453;MGI:3578624;HomoloGene:56919;GeneCards:ITGAD;OMA:ITGAD - orthologs

Gene location (Human)

Chr.	Chromosome 16 (human)^[1]

Band	16p11.2	Start	31,393,335bp^[1]
Band	16p11.2	End	31,426,505bp^[1]

Gene location (Mouse)

Chr.	Chromosome 7 (mouse)^[2]

Band	7\|7 F3	Start	127,753,548bp^[2]
Band	7\|7 F3	End	127,822,988bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

granulocyte

spleen

gastrocnemius muscle

lymph node

muscle of thigh

appendix

blood

decidua

right lobe of liver

gallbladder

Top expressed in

spleen

spermatid

testicle

spermatocyte

islet of Langerhans

bone marrow

embryo

granulocyte

thymus

primary oocyte

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	metal ion binding protein heterodimerization activity
Cellular component	integral component of membrane cell surface integrin complex plasma membrane membrane
Biological process	integrin-mediated signaling pathway heterotypic cell-cell adhesion extracellular matrix organization cell adhesion immune response
Sources:Amigo /QuickGO

Orthologs

Species

Human

Mouse

Entrez


3681


381924

Ensembl


ENSG00000156886


ENSMUSG00000070369

UniProt


Q13349


Q3V0T4

RefSeq (mRNA)


NM_005353 NM_001318185


NM_001029872 NM_001177632

RefSeq (protein)


NP_001305114 NP_005344


NP_001025043

Location (UCSC)

Chr 16: 31.39 – 31.43 Mb

Chr 7: 127.75 – 127.82 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Integrin alpha-D is aprotein that inhumans isencoded by theITGADgene.^[5]^[6]^[7]

References

[edit]

^^a ^b ^cGRCh38: Ensembl release 89: ENSG00000156886 –Ensembl, May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000070369 –Ensembl, May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Wong DA, Davis EM, LeBeau M, Springer TA (Aug 1996). "Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit".Gene.171 (2):291–4.doi:10.1016/0378-1119(95)00869-1.PMID 8666289.
^Shelley CS, Da Silva N, Georgakis A, Chomienne C, Arnaout MA (Aug 1998). "Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb".Genomics.49 (2):334–6.doi:10.1006/geno.1998.5232.PMID 9598326.
^"Entrez Gene: ITGAD integrin, alpha D".

External links

[edit]

ITGAD Info with links in theCell Migration Gateway Archived 2014-12-11 at theWayback Machine

Integrins

Alpha

Beta

Dimers

Cytoadhesin receptor:	Integrin alpha6beta4 Glycoprotein IIb/IIIa ITGA2B+ITGB3
Fibrinogen receptor:	Macrophage-1 antigen CD11b+CD18
Fibronectin receptor:	Integrin alpha2beta1 Integrin alpha4beta1 Integrin alpha5beta1
Leukocyte-adhesion receptor:	LFA-1 CD11a+CD18 Macrophage-1 antigen CD11b+CD18 Integrin alphaXbeta2 CD11c+CD18
Very late antigen receptor:	Integrin alpha1beta1 Integrin alpha2beta1 Integrin alpha3beta1 VLA-4 CD49d+CD29 Alpha-5 beta-1 Integrin alpha6beta1
Vitronectin receptor:	Alpha-v beta-3 Alpha-v beta-5

see alsocell surface receptor deficiencies

v t e Proteins:clusters of differentiation (see alsolist of human clusters of differentiation)
1–50	CD1 a-c 1A 1B 1D 1E CD2 CD3 γ δ ε CD4 CD5 CD6 CD7 CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50
51–100	CD51 CD52 CD53 CD54 CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85 a d e h j k CD86 CD87 CD88 CD89 CD90 CD91 -CD92 CD93 CD94 CD95 CD96 CD97 CD98 CD99 CD100
101–150	CD101 CD102 CD103 CD104 CD105 CD106 CD107 a b CD108 CD109 CD110 CD111 CD112 CD113 CD114 CD115 CD116 CD117 CD118 CD119 CD120 a b CD121 a b CD122 CD123 CD124 CD125 CD126 CD127 CD129 CD130 CD131 CD132 CD133 CD134 CD135 CD136 CD137 CD138 CD140b CD141 CD142 CD143 CD144 CD146 CD147 CD148 CD150
151–200	CD151 CD152 CD153 CD154 CD155 CD156 a b c CD157 CD158 (a d e i k) CD159 a c CD160 CD161 CD162 CD163 CD164 CD166 CD167 a b CD168 CD169 CD170 CD171 CD172 a b g CD174 CD177 CD178 CD179 a b CD180 CD181 CD182 CD183 CD184 CD185 CD186 CD191 CD192 CD193 CD194 CD195 CD196 CD197 CDw198 CDw199 CD200
201–250	CD201 CD202b CD204 CD205 CD206 CD207 CD208 CD209 CDw210 a b CD212 CD213a 1 2 CD217 CD218 (a b) CD220 CD221 CD222 CD223 CD224 CD225 CD226 CD227 CD228 CD229 CD230 CD233 CD234 CD235 a b CD236 CD238 CD239 CD240CE CD240D CD241 CD243 CD244 CD246 CD247 -CD248 CD249
251–300	CD252 CD253 CD254 CD256 CD257 CD258 CD261 CD262 CD263 CD264 CD265 CD266 CD267 CD268 CD269 CD271 CD272 CD273 CD274 CD275 CD276 CD278 CD279 CD280 CD281 CD282 CD283 CD284 CD286 CD288 CD289 CD290 CD292 CDw293 CD294 CD295 CD297 CD298 CD299
301–350	CD300A CD301 CD302 CD303 CD304 CD305 CD306 CD307 CD309 CD312 CD314 CD315 CD316 CD317 CD318 CD320 CD321 CD322 CD324 CD325 CD326 CD327 CD328 CD329 CD331 CD332 CD333 CD334 CD335 CD336 CD337 CD338 CD339 CD340 CD344 CD349 CD350

This article on agene on humanchromosome 16 is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Integrin_alpha_D&oldid=1194909821"

Categories:

Hidden categories:

[8]ページ先頭

Movatterモバイル変換

References

Further reading

External links