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Integrin alpha 8

From Wikipedia, the free encyclopedia
(Redirected fromITGA8)
Protein-coding gene in the species Homo sapiens

ITGA8
Identifiers
AliasesITGA8, integrin subunit alpha 8
External IDsOMIM:604063;MGI:109442;HomoloGene:37396;GeneCards:ITGA8;OMA:ITGA8 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for ITGA8
Genomic location for ITGA8
Band10p13Start15,513,954bp[1]
End15,719,922bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for ITGA8
Genomic location for ITGA8
Band2 A1|2 9.12 cMStart12,111,443bp[2]
End12,306,733bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Descending thoracic aorta

  • ascending aorta

  • urethra

  • right coronary artery

  • saphenous vein

  • gastric mucosa

  • popliteal artery

  • tibial arteries

  • left coronary artery

  • vena cava
Top expressed in
  • ascending aorta

  • aortic valve

  • carotid body

  • right lung lobe

  • vas deferens

  • tunica media of zone of aorta

  • left lung lobe

  • vestibular membrane of cochlear duct

  • efferent ductule

  • conjunctival fornix
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8516

241226

Ensembl

ENSG00000077943

ENSMUSG00000026768

UniProt

P53708

A2ARA8

RefSeq (mRNA)

NM_001291494
NM_003638

NM_001001309

RefSeq (protein)

NP_001278423
NP_003629

NP_001001309
NP_001395029
NP_001395030
NP_001395031

Location (UCSC)Chr 10: 15.51 – 15.72 MbChr 2: 12.11 – 12.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Integrin alpha-8 is aprotein that in humans is encoded by theITGA8gene.[5][6]


References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000077943Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000026768Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Schnapp LM, Breuss JM, Ramos DM, Sheppard D, Pytela R (Jul 1995). "Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells".J Cell Sci.108 (2):537–44.doi:10.1242/jcs.108.2.537.PMID 7768999.
  6. ^"Entrez Gene: ITGA8 integrin, alpha 8".

Further reading

[edit]

External links

[edit]
Alpha
Beta
Dimers
Cytoadhesin receptor:
Fibrinogen receptor:
Fibronectin receptor:
Leukocyte-adhesion receptor:
Very late antigen receptor:
Vitronectin receptor:


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