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IL1F10

From Wikipedia, the free encyclopedia

Human protein and coding gene
"IL-38" redirects here. For the aircraft, seeIlyushin Il-38. For the road, seeIllinois Route 38.
IL1F10
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

5BOW

Identifiers
AliasesIL1F10, FIL1-theta, IL-1HY2, IL-38, IL1-theta, IL1HY2, FKSG75, interleukin 1 family member 10 (theta), interleukin 1 family member 10
External IDsOMIM:615296;MGI:2652548;HomoloGene:17690;GeneCards:IL1F10;OMA:IL1F10 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for IL1F10
Genomic location for IL1F10
Band2q14.1Start113,067,970bp[1]
End113,075,843bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for IL1F10
Genomic location for IL1F10
Band2 A3|2 16.32 cMStart24,181,208bp[2]
End24,183,832bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of limb

  • skin of leg

  • skin of abdomen

  • skin of thigh

  • human penis

  • amniotic fluid

  • gonad

  • pharynx

  • tonsil

  • placenta
Top expressed in
  • lip

  • skin of abdomen

  • skin of external ear

  • skin of back

  • hair follicle

  • cervix

  • thymus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84639

215274

Ensembl

ENSG00000136697

ENSMUSG00000046845

UniProt

Q8WWZ1

Q8R459

RefSeq (mRNA)

NM_173161
NM_032556

NM_153077

RefSeq (protein)

NP_115945
NP_775184

NP_694717

Location (UCSC)Chr 2: 113.07 – 113.08 MbChr 2: 24.18 – 24.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin-1 family member 10 is aprotein that in humans is encoded by theIL1F10gene.[5][6][7][8]

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.[8]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000136697Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000046845Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Bensen JT, Dawson PA, Mychaleckyj JC, Bowden DW (Dec 2001). "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14".J Interferon Cytokine Res.21 (11):899–904.doi:10.1089/107999001753289505.PMID 11747621.
  6. ^Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002). "Genomic organization of the interleukin-1 locus".Genomics.79 (5):726–33.doi:10.1006/geno.2002.6752.PMID 11991723.
  7. ^Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002). "A sequence-based map of the nine genes of the human interleukin-1 cluster".Genomics.79 (5):718–25.doi:10.1006/geno.2002.6751.PMID 11991722.
  8. ^ab"Entrez Gene: IL1F10 interleukin 1 family, member 10 (theta)".

Further reading

[edit]
By family
Chemokine
CCL
CXCL
CX3CL
XCL
TNF
Interleukin
Type I
(grouped by
receptor
subunit)
γ chain
β chain
IL6 like/gp130
IL12 family/IL12RB1
Other
Type II
IL10 family
Interferon
I
II
Ig superfamily
IL17 family
Other
By function/
cell
IL-1
IL-2
IL-3
IL-4
IL-5
IL-6
IL-7
IL-8
  • See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ)here instead.
IL-9
IL-10
IL-11
IL-12
IL-13
IL-15
IL-17
IL-18
IL-20
IL-21
IL-22
IL-23
IL-27
IL-28
IL-31
IL1RL1
IL1RL2
Others
JAK
Others
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