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IGFBP6

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
IGFBP6
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

1RMJ

Identifiers
AliasesIGFBP6, IBP6, insulin like growth factor binding protein 6
External IDsOMIM:146735;MGI:96441;HomoloGene:1641;GeneCards:IGFBP6;OMA:IGFBP6 - orthologs
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[1]
Chromosome 15 (mouse)
Genomic location for IGFBP6
Genomic location for IGFBP6
Band15|15 F2Start102,052,797bp[1]
End102,057,946bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • tibial nerve

  • gastric mucosa

  • canal of the cervix

  • left uterine tube

  • right coronary artery

  • thoracic aorta

  • ascending aorta

  • trigeminal ganglion

  • left coronary artery
Top expressed in
  • ankle

  • uterus

  • right lung

  • right lung lobe

  • ankle joint

  • cervix

  • left lung

  • lip

  • white adipose tissue

  • esophagus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

3489

16012

Ensembl

n/a

ENSMUSG00000023046

UniProt

P24592

P47880

RefSeq (mRNA)

NM_002178

NM_008344

RefSeq (protein)

NP_002169

NP_032370

Location (UCSC)n/aChr 15: 102.05 – 102.06 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Insulin-like growth factor-binding protein 6 (IGFBP-6) is aprotein that in humans is encoded by theIGFBP6gene.[4][5][6]

References

[edit]
  1. ^abcGRCm38: Ensembl release 89: ENSMUSG00000023046Ensembl, May 2017
  2. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^Kiefer MC, Ioh RS, Bauer DM, Zapf J (May 1991). "Molecular cloning of a new human insulin-like growth factor binding protein".Biochem Biophys Res Commun.176 (1):219–25.doi:10.1016/0006-291X(91)90912-Q.PMID 1850258.
  5. ^Ehrenborg E, Zazzi H, Lagercrantz S, Granqvist M, Hillerbrand U, Allander SV, Larsson C, Luthman H (May 1999). "Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene".Mamm Genome.10 (4):376–80.doi:10.1007/s003359901005.PMID 10087296.S2CID 21499958.
  6. ^"Entrez Gene: IGFBP6 insulin-like growth factor binding protein 6".

Further reading

[edit]
PDB gallery
  • 2jm2: Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs
    2jm2: Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs
Fatty acid
Hormone
Metal/element
Vitamin
Pigment
Other
Angiopoietin
CNTF
EGF (ErbB)
EGF
(ErbB1/HER1)
ErbB2/HER2
ErbB3/HER3
ErbB4/HER4
FGF
FGFR1
FGFR2
FGFR3
FGFR4
Unsorted
HGF (c-Met)
IGF
IGF-1
IGF-2
Others
LNGF (p75NTR)
PDGF
RET (GFL)
GFRα1
GFRα2
GFRα3
GFRα4
Unsorted
SCF (c-Kit)
TGFβ
Trk
TrkA
TrkB
TrkC
VEGF
Others


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