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Hydroxycarteolol

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Chemical compound

Pharmaceutical compound

Hydroxycarteolol
Clinical data

Other names	8-Hydroxycarteolol
ATC code	None
Identifiers
IUPAC name 8-Hydroxy-5-{2-hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone
CAS Number	59826-22-1
PubChemCID	124688
ChemSpider	111020
ChEBI	CHEBI:192312
CompTox Dashboard(EPA)	DTXSID50975219
Chemical and physical data
Formula	C₁₆H₂₄N₂O₄
Molar mass	308.378 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C2Nc1c(O)ccc(OCC(O)CNC(C)(C)C)c1CC2
InChI InChI=1S/C16H24N2O4/c1-16(2,3)17-8-10(19)9-22-13-6-5-12(20)15-11(13)4-7-14(21)18-15/h5-6,10,17,19-20H,4,7-9H2,1-3H3,(H,18,21) Key:TVZJLAKRXHGVOK-UHFFFAOYSA-N

Hydroxycarteolol is abeta blocker and metabolite ofcarteolol.^[1]^[2]

^Igarashi H, Katsuta Y, Sawa K, Nakazato Y, Kawasaki T (Apr 1990). "A comparison of the opacifying effects of carteolol.HCl and 8-hydroxycarteolol.HCl in the isolated porcine cornea".Fundam Appl Toxicol.14 (3):554–559.doi:10.1093/toxsci/14.3.554.PMID 2340982.
^Jasper JR, Michel MC, Insel PA (1990)."The beta-adrenoceptor antagonist carteolol and its metabolite 8-hydroxycarteolol have different intrinsic sympathomimetic activities".Br J Clin Pharmacol.30 (Suppl 1):109S–111S.doi:10.1111/j.1365-2125.1990.tb05477.x.PMC 1368107.PMID 2176514.

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