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| Names | |
|---|---|
| IUPAC name 2(1H-4,4-dimethyl tetrahydro pyrimidinylidene ) (3-(4-(trifluoromethyl)phenyl)-1-(2-(4-(trifluoromethyl)phenyl)ethenyl) -2-propenylidene)hydrazone | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.100.669 |
| KEGG |
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| UNII | |
| |
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| Properties | |
| C25H24F6N4 | |
| Molar mass | 494.485 g·mol−1 |
| Appearance | Yellow to orange crystalline solid |
| Melting point | 185 to 190 °C (365 to 374 °F; 458 to 463 K) |
| Hazards | |
| NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Hydramethylnon (AC 217,300) is aninsecticide used primarily in the form ofbaits forcockroaches andants.[1][2][3] It works by inhibitingcomplex III in the mitochondrial inner membrane and leads to a halting ofoxidative phosphorylation (IRAC class 20A). Some brands of hydramethylnon areAmdro, Blatex, Combat, Cyaforce, Cyclon, Faslane, Grant's, Impact, Matox, Maxforce, Pyramdron, Siege, Scuttle and Wipeout. Hydramethylnon is a slow-acting poison with delayed toxicity that needs to be eaten to be effective.[4]
Hydramethylnon has low toxicity in mammals.[2][4] The oralLD50 is 1100–1300 mg/kg in rats and above 28,000 mg/kg in dogs.[4] Hydramethylnon istoxic to fish; the 96-hour LC50 in rainbow trout is 0.16 mg/L, 0.10 mg/L inchannel catfish, and 1.70 mg/L inbluegill sunfish.
Hydramethylnon, when fed to rats for two years, led to an increase inuterine andadrenal tumors at the highest dose; therefore, theEnvironmental Protection Agency classifies hydramethylnon as a possible human carcinogen.[4]
