Homer William Smith | |
|---|---|
| Born | (1895-01-02)January 2, 1895 |
| Died | March 25, 1962(1962-03-25) (aged 67) |
| Education | Johns Hopkins University (DSc 1921) |
| Known for | Study of kidney function |
| Awards | Albert Lasker Award for Basic Medical Research (1947) |
| Scientific career | |
| Fields | Physiologist,science writer |
| Institutions | New York University School of Medicine |
Homer William Smith (January 2, 1895 – March 25, 1962) was an Americanphysiologist andscience writer known for his experiments on thekidney and philosophical writings onnatural history and the theory ofevolution.[1]
Smith was born on January 2, 1895, inDenver, and three years later, his family moved toCripple Creek, Colorado, which was included in both theCripple Creek miners' strike of 1894 and theColorado Labor Wars of 1903–04. He had a stutter from about the age of five, to which he attributes his introspectiveness.[2] Smith's mother died by the time he was seven; he had five older siblings at the time, the oldest of which was 26.[3] Smith describes his father as "of the generation that had one foot still planted inreligious tradition, the other planted in irreligiousrationalism. ... For his mixed sentiment and skepticism my father paid off his conscience by generous hospitality, and any minister of any gospel was welcome at his table."[4]
At the age of eleven, while Smith had themeasles, his father built him a shed in which he could conduct scientific experiments;[5] these involved chemistry andmicrobiology, as well as the use of avacuum pump,telegraph,static machine,X-ray tube, andTesla coil.[6] He also dissected cats, which fueled his interest for biology and diminished his faith inanthropocentrism.[7] As a result of the apathy he felt following thesinking of the RMS Titanic on April 15, 1912, he set out on a philosophical quest of reading and writing with a renewed focus towards scholarship.[8]
Smith received hisD.Sc in 1921 fromJohns Hopkins University School of Hygiene and Public Health. From 1928 until his retirement in 1961 he was the Professor of Physiology and Director of the Physiological Laboratories atNew York University School of Medicine.[9] Smith was a leader in the field ofrenal physiology.[10] His elegant experiments on the kidney in the 1930s proved beyond any doubt that it operated according to physical principles, both as a filter and a secretory organ, eliminating the last vestige ofvitalism in physiology.[11] He usedinulin (at the same time asA. N. Richards) to measure how much kidney filtrate is formed. His bookThe Kidney: Structure and Function in Health and Disease (1951) was an authoritative summary of what was known at that time.
Komongo or, the Lungfish and the Padre (1932) takes place in theSuez Canal where a scientist returning to the United States with a cargo of lungfish for kidney experiments delivers a monologue to an Anglican Minister on howevolution shapes organisms. The book, after being personally rejected byAlfred A. Knopf, was accepted byViking Press. It became aBook of the Month, was included inThe Woollcott Reader (1935), and republished as a Pocket Overseas Edition for the troops duringWorld War II, and then made a monthly selection by the Natural History Book Club. For the latter republication, the book had to be reset, as the original plates had been donated during the metal shortages of 1943–44. Smith desired to make changes to the book, which the publisher gave him a week to make.[12][a]
The manuscript forMan and His Gods (1952), which Smith describes as "a simple story of man's changing ideas about himself and his place in nature," was declined by several publishers and reduced from about 275,000 to 250,000 words before it was accepted byLittle, Brown and Company. The publisher made further cuts for length, which Smith approved of.[12] It considers "man's ideas about the supernatural in the perspective of the evolution of western theology and philosophy from theancient Egyptians to the nineteenth century",[14][11] culminating inDarwin's theory of evolution and thereaction to it, including the thoughts ofThomas Henry Huxley and the relationship of modern thought to that of pre-evolutionist philosophersJohn Locke,David Hume andImmanuel Kant.[15][b]Albert Einstein says in the foreword:
The work is a broadly conceived attempt to portray man's fear-induced animistic and mythic ideas with all their far-flung transformations and interrelations. It relates the impact of these phantasmagorias on human destiny and the causal relationships by which they have come to be crystallized into organized religion. This is a biologist speaking whose scientific training has disciplined him in a grim objectivity rarely found in the pure historian.[17]
From Fish to Philosopher (1953) explains how evolutionary history accounts for the seemingly bewilderingmammalian kidney, in which water, salts, and small molecules are filtered from the blood into kidney tubules and then much of the water and salt and many of the small molecules are pumped back into the blood stream. He argues that vertebrates originated in fresh water, where water was drawn into their bodies by theosmotic pressure of their body fluids; their kidneys excreted the extra water while also retrieving their supply of small solutes.
Smith served on the board of trustees of Science Service, now known asSociety for Science & the Public, from 1952–1955.[11]
Smith died on March 25, 1962, at the age of 67.
As a memorial to Smith in 1963 theNew York Heart Association created the Homer W. Smith Award in Renal Physiology.[18] Additionally, the American Society of Nephrology established The Homer Smith Award in 1964. The award is presented annually to an individual who has made outstanding contributions which fundamentally affect the science of nephrology, broadly defined, but not limited to, the pathobiology, cellular and molecular mechanisms and genetic influences on the functions and diseases of the kidney.
Homer Smith was married to Margaret Wilson, who was the daughter of Lily and James Robert Wilson from Spring City, Tennessee. His son was Homer Wilson Smith.[11]
Smith attackedsuperstition and was critical ofreligious ideas.[19] He wasagnostic[20][21] and an advocate of theChrist myth theory.[22][23]
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