| Hippocampal sulcus | |
|---|---|
.jpg) Hippocampal sulcus labeled at center. | |
| Details | |
| Identifiers | |
| Latin | sulcus hippocampalis, sulcus hippocampi |
| NeuroNames | 42 |
| NeuroLex ID | birnlex_4004 |
| TA98 | A14.1.09.236 |
| TA2 | 5522 |
| FMA | 83747 |
| Anatomical terms of neuroanatomy | |
Thehippocampal sulcus, also known as thehippocampal fissure, is asulcus that separates thedentate gyrus from thesubiculum and the CA1 field in thehippocampus.
During humanfetal development, the hippocampal sulcus first appears at approximately 10 weeks ofgestational age. At this stage it exists as a broad shallow fissure along the surface of the dentate gyrus. Gradually, the fissure deepens and shifts toward thecornu ammonis. After about 18 weeks, the walls of the fissure fold into each other and begin to fuse. By 30 weeks, the hippocampal sulcus is normally obliterated except for its most medial part, leaving a shallow surface indentation.[1]
Enlargement of the hippocampal sulcus has been associated with medialtemporal lobeatrophy occurring inAlzheimer's disease.[2]
