This is a list ofAmerican football players who played only one game in theNational Football League (NFL) during the league's first decade from1920 to the1929. This list includes players from theAmerican Professional Football Association (APFA) during the 1920 and 1921 seasons, i.e., before the APFA was renamed the NFL in 1922. This list does not include those who were on an active roster but never actually appeared in a game. Nor does it include those who appeared only in a pre-season or exhibition game.

• Date - The "Date" column is intended to provide the date of the player's appearance in an NFL game. If the exact date has not yet been verified, then the column simply lists the year.
• Start - The "Start" column is intended to state whether or not the player's appearance in an NFL game was as a "starter". If the player appeared in the game as a substitute, the entry should state "No".

• List of players who appeared in only one game in the NFL (1930–1939)

• Lists of NFL players

• Articles with short description
• Short description is different from Wikidata