Halogenodermas are skin eruptions that result after exposure tohalogen-containing drugs or substances. This may last several weeks after drug use is discontinued. This is because of theslow elimination rate ofiodides andbromides.[1] Fluoroderma is a particular type of halogenoderma which is caused byfluoride.Fluoride is present in oral hygiene products such as toothpastes and mouth washes, hence this type of acne is seen mostly around the mouth and jawline. Acute fluoroderma has been observed in patients exposed toanaesthetics containingfluoride such assevoflurane.[2]
The most common presentation of halogenoderma ispustules orpapulopustular lesions, which are often found on the face, neck, back, and limbs.[3] In some cases, halogenoderma manifests as large vegetating lesions as opposed to pustular eruption.[4]
Iodide andbromide-containing substances should be avoided when treating halogenoderma. Lesions typically go away on their own four to six weeks afteriodide orbromide intake is stopped.[6] It is possible to use systemiccorticosteroids to help these lesions heal more quickly.[7]
^Guerrero, Arthur F.; Guerrero, Karen T.; Shakir, K.M. Mohamed (2011). "Thyroid Protection Gone Awry: Iododerma Following Potassium Iodide Administration Prior to Metaiodobenzylguanidine Scintigraphy".Thyroid.21 (1). Mary Ann Liebert Inc:93–94.doi:10.1089/thy.2009.0467.ISSN1050-7256.PMID21162686.
^Didona, D.; Solimani, F.; Mühlenbein, S.; Knake, S.; Mittag, H.; Pfützner, W. (October 8, 2019). "Diffuse vegetating bromoderma".Journal of the European Academy of Dermatology and Venereology.34 (2). Wiley:e53 –e55.doi:10.1111/jdv.15899.ISSN0926-9959.PMID31433883.S2CID201276655.
