Inhistology, theHPS stain, orhematoxylinphloxinesaffronstain, is a way of markingtissues.
HPS is similar toH&E, thestandard bearer in histology. However, it differentiates between the most commonconnective tissue (collagen) andmuscle andcytoplasm by staining the former yellow and the latter two pink,[1] unlike an H&E stain, which stains all three pink.
HPS stained sections are more expensive than H&E stained sections, primarily due to the cost of saffron.