This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.[6]
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Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B (1996). "Fine mapping of human HOX gene clusters".Cytogenetics and Cell Genetics.73 (1–2):114–5.doi:10.1159/000134320.PMID8646877.
Flagiello D, Gibaud A, Dutrillaux B, Poupon MF, Malfoy B (October 1997). "Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines".FEBS Letters.415 (3):263–7.Bibcode:1997FEBSL.415..263F.doi:10.1016/S0014-5793(97)01118-6.PMID9357979.S2CID26075369.
Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, Tomita M, McGinnis W, Matsuo N (February 2002). "Complete mutation analysis panel of the 39 human HOX genes".Teratology.65 (2):50–62.doi:10.1002/tera.10009.PMID11857506.
Okamoto OK, Oba-Shinjo SM, Lopes L, Nagahashi Marie SK (2007). "Expression of HOXC9 and E2F2 are up-regulated in CD133(+) cells isolated from human astrocytomas and associate with transformation of human astrocytes".Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression.1769 (7–8):437–42.doi:10.1016/j.bbaexp.2007.05.002.PMID17588684.
