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| Other names | 4-Propylthio-2,5-dimethoxy-N-hydroxyphenethylamine; 2,5-Dimethoxy-4-propylthio-N-hydroxyphenethylamine;N-Hydroxy-2C-T-7;N-OH-2C-T-7 |
| Routes of administration | Oral[1] |
| Drug class | Serotonergic psychedelic;Hallucinogen |
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| Pharmacokinetic data | |
| Metabolites | Possibly2C-T-7[1][2] |
| Onset of action | Unknown[1] |
| Duration of action | 6–8 hours[1] |
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| Chemical and physical data | |
| Formula | C13H21NO3S |
| Molar mass | 271.38 g·mol−1 |
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HOT-7, also known as4-propylthio-2,5-dimethoxy-N-hydroxyphenethylamine or asN-hydroxy-2C-T-7, is apsychedelic drug of thephenethylamine,2C, andHOT-x families.[1] It is theN-hydroxyderivative of2C-T-7.[1] The drug is takenorally.[1]
In his bookPiHKAL (Phenethylamines I Have Known and Loved),Alexander Shulgin lists HOT-7's dose range as 15 to 20 mgorally and itsduration as 6 to 8 hours.[1] The drug'sonset and peak of effects were not described.[1] HOT-7's properties are similar to those of2C-T-7, which has a dose of 10 to 30 mg orally and a duration of 8 to 15 hours, although HOT-7 may have a somewhat shorter duration.[1][2] HOT-7 may act as aprodrug of 2C-T-7.[2]
The effects of HOT-7 have been reported to include being "quitepsychedelic", very rich inclosed-eyeimagery, not as much in terms ofopen-eye visuals, very good for interpretive and conceptual thinking,emotional changes, feeling "smoothlystoned",lightheadedness,alcohol-liketipsiness andwooziness,social avoidance, andgastrointestinal disturbances.[1]
Thechemical synthesis of HOT-7 has been described.[1]
Analogues of HOT-7 include2C-T-7,HOT-2 (N-hydroxy-2C-T-2), andHOT-17 (N-hydroxy-2C-T-17), among others.[1]
HOT-7 was first described in the literature byAlexander Shulgin in his 1991 bookPiHKAL (Phenethylamines I Have Known and Loved).[1]
This substance is a Class A drug in theDrugs controlled by the UK Misuse of Drugs Act.[3]
