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Guvacoline

From Wikipedia, the free encyclopedia
Guvacoline
Names
Preferred IUPAC name
Methyl 1,2,5,6-tetrahydropyridine-3-carboxylate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C7H11NO2/c1-10-7(9)6-3-2-4-8-5-6/h3,8H,2,4-5H2,1H3
    Key: DYPLDWLIOGXSSE-UHFFFAOYSA-N
  • COC(=O)C1=CCCNC1
Properties
C7H11NO2
Molar mass141.170 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Guvacoline is a compound with thechemical formula C7H11NO2.[1] It is a component ofAreca nut and a precursor ofguvacine. It agonizesmuscarinic receptors just like arecoline but unlike arecoline it lacksnicotinic activity.[2]

See also

[edit]

References

[edit]
  1. ^PubChem."Guvacoline".pubchem.ncbi.nlm.nih.gov. Retrieved2020-06-14.
  2. ^Horenstein NA, Quadri M, Stokes C, Shoaib M, Papke RL (May 2019)."Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds".Nicotine & Tobacco Research.21 (6):805–812.doi:10.1093/ntr/ntx187.PMC 6528145.PMID 29059390.
mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(andprodrugs)


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