Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

Gil McVean

From Wikipedia, the free encyclopedia
British statistical geneticist (born 1973)

Gil McVean
McVean in 2016
Born
Gilean Alistair Tristram McVean

February 1973 (age 52)
Alma mater
Awards
Scientific career
Institutions
ThesisAdaptation and conflict : the differences between the sexes in mammalian genome evolution (1998)
Doctoral advisorLaurence Hurst[2][3][4]
Other academic advisors
WebsiteProfessor Gil McVean - University of Oxford

Gilean Alistair Tristram McVean (born February 1973)[5] is a professor of statisticalgenetics at theUniversity of Oxford,[6] fellow ofLinacre College, Oxford and co-founder and director ofGenomics plc.[5][7] He also co-chaired the1000 Genomes Project analysis group.[8][9]

Education

[edit]
Gilean McVean speaking at the 2010 GEM meeting at theWellcome Trust Sanger Institute, Hinxton

From 1991-94, he completed aBachelor of Arts degree in Biological Sciences at the University of Oxford.[10] He completed hisPhD in the Department of Genetics at theUniversity of Cambridge supervised byLaurence Hurst[11][12] in 1998.[3][13]

Career and research

[edit]

McVean completedpostdoctoral research at theUniversity of Edinburgh from 1997 to 2000, supervised byBrian andDeborah Charlesworth.[14][13]

From 2000-04, he was aRoyal Society University Research Fellow in the Department of Statistics at Oxford, where he has also been a University lecturer in Mathematical Genetics since 2004. He was reappointed in 2009 until retirement age.[15] In October 2006, he was appointed professor of statistical genetics at the University of Oxford.[16]

McVean's research[17] focuses onpopulation genetics, statistics[18] andevolutionary biology including theInternational HapMap Project,[19][20] recombination rates in thehuman genome[21] and the1000 Genomes Project.[22][23]

McVean developed a statistical method to look at recombination rate which helped to identifyPRDM9 as a hotspot positioning gene.[24] In 2014, withPeter Donnelly, McVean co-founded Genomics plc, a genomics analysis company, as acorporate spin-off of the University of Oxford.[5] In 2017, he was a founding director of theBig Data Institute at the University of Oxford.[25]

Honours and awards

[edit]

In 2006 McVean was awarded aPhilip Leverhulme Prize.[26][27]

In 2010, McVean was awarded theFrancis Crick Medal and delivered that year's lecture entitled "Our genomes, our history".[28]

In 2012, he was awarded theWeldon Memorial Prize.[29]

In 2013, he presented a talk TEDxWarwick entitledA Thousand Genomes a Thousand Stories.[30]

In May 2014, McVean was elected as a member of theEuropean Molecular Biology Organisation.[31]

McVean was electedFellow of the Royal Society (FRS) in 2016[32] and aFellow of the Academy of Medical Sciences (FMedSci).[33][34]

References

[edit]
  1. ^"Francis Crick Medal and Lecture 2010 - Our genomes, our history".Royal Society. Retrieved27 January 2022.
  2. ^Hurst, L.; McVean, G. (1996)."A difficult phase for introns-early. Molecular evolution".Current Biology.6 (5):533–36.doi:10.1016/S0960-9822(02)00535-3.PMID 8805261.
  3. ^abMcVean, Gilean Alistair Tristram (1998).Adaptation and conflict: the differences between the sexes in mammalian genome evolution (PhD thesis). University of Cambridge.OCLC 894602716. Archived fromthe original on 11 February 2022. Retrieved15 May 2015.
  4. ^"Students and post-docs past and present in the Hurst laboratory". University of Bath. Archived fromthe original on 15 May 2015.
  5. ^abcAnon (2016)."Gilean MCVEAN Profile".companieshouse.gov.uk. London:Companies House. Archived fromthe original on 12 August 2016.
  6. ^"McVean Group at the University of Oxford". Archived fromthe original on 29 January 2009. Retrieved19 February 2009.
  7. ^"Prof. Gil McVean - GENOMICS plc". Archived fromthe original on 28 October 2017. Retrieved30 December 2017.
  8. ^"Oct 10: 1000 Genomes project - Wellcome Trust Centre for Human Genetics".www.well.ox.ac.uk. Archived fromthe original on 10 September 2018. Retrieved30 December 2017.
  9. ^Gil McVean publications fromEurope PubMed Central
  10. ^Gil McVean'sORCID 0000-0002-5012-4162
  11. ^McVean, G.T.; Hurst, L.D. (1997). "Evidence for a selectively favourable reduction in the mutation rate of the X chromosome".Nature.386 (6623):388–92.Bibcode:1997Natur.386..388M.doi:10.1038/386388a0.PMID 9121553.S2CID 4343123.
  12. ^Hurst, L.D.; McVean, G.T. (1996)."...And scandalous symbionts".Nature.381 (6584):650–51.Bibcode:1996Natur.381..650H.doi:10.1038/381650a0.PMID 8649507.
  13. ^ab"Gilean McVean profile".Oxford University. Archived fromthe original on 24 October 2017. Retrieved30 December 2017.
  14. ^Charlesworth, D.; Charlesworth, B.; McVean, G. (2001). "Genome sequences and evolutionary biology, a two-way interaction".Trends in Ecology & Evolution.16 (5):235–42.doi:10.1016/S0169-5347(01)02126-7.PMID 11301152.
  15. ^"Oxford University Gazette - Reappointments".ox.ac.uk. 14 May 2009. Archived fromthe original on 30 May 2009. Retrieved30 December 2017.
  16. ^"Oxford University Gazette".ox.ac.uk. Archived fromthe original on 2 October 2013. Retrieved12 July 2016.
  17. ^Gilean McVean profile,Google Scholar; accessed 30 December 2017.
  18. ^Reshef, D. N.; Reshef, Y. A.; Finucane, H. K.; Grossman, S. R.;McVean, G.; Turnbaugh, P. J.;Lander, E. S.; Mitzenmacher, M.;Sabeti, P. C. (2011)."Detecting Novel Associations in Large Data Sets".Science.334 (6062):1518–1524.Bibcode:2011Sci...334.1518R.doi:10.1126/science.1205438.PMC 3325791.PMID 22174245.
  19. ^Frazer, K. A.; Frazer, D. G.; Ballinger, D. R.; Cox, D. A.; Hinds, L. L.; Stuve, R. A.; Gibbs, J. W.; Belmont, A.; Boudreau, P.; Hardenbol, S. M.; Leal, S.; Pasternak, D. A.; Wheeler, T. D.; Willis, F.; Yu, H.; Yang, C.; Zeng, Y.; Gao, H.; Hu, W.; Hu, C.; Li, W.; Lin, S.; Liu, H.; Pan, X.; Tang, J.; Wang, W.; Wang, J.; Yu, B.; Zhang, Q.; et al. (2007)."A second generation human haplotype map of over 3.1 million SNPs".Nature.449 (7164):851–61.Bibcode:2007Natur.449..851F.doi:10.1038/nature06258.PMC 2689609.PMID 17943122.
  20. ^Sabeti, Pardis C.; Varilly, Patrick; Fry, Ben; Lohmueller, Jason; Hostetter, Elizabeth; Cotsapas, Chris; Xie, Xiaohui; Byrne, Elizabeth H.; McCarroll, Steven A.; Gaudet, Rachelle; Schaffner, Stephen F.; Lander, Eric S.; The International HapMap Consortium; Frazer, Kelly A.; Ballinger, Dennis G.; Cox, David R.; Hinds, David A.; Stuve, Laura L.; Gibbs, Richard A.; Belmont, John W.; Boudreau, Andrew; Hardenbol, Paul; Leal, Suzanne M.; Pasternak, Shiran; Wheeler, David A.; Willis, Thomas D.; Yu, Fuli; Yang, Huanming; Zeng, Changqing Zeng; et al. (2007)."Genome-wide detection and characterization of positive selection in human populations".Nature.449 (7164):913–918.Bibcode:2007Natur.449..913S.doi:10.1038/nature06250.PMC 2687721.PMID 17943131.
  21. ^McVean, G. A. T.; Myers, S.; Hunt, S.; Deloukas, P.; Bentley, D.; Donnelly, P. (2004). "The Fine-Scale Structure of Recombination Rate Variation in the Human Genome".Science.304 (5670):581–584.Bibcode:2004Sci...304..581M.doi:10.1126/science.1092500.PMID 15105499.S2CID 20616898.
  22. ^Danecek, P.; Auton, A.; Abecasis, G.; Albers, C. A.; Banks, E.; Depristo, M. A.; Handsaker, R.; Lunter, G.; Marth, G.; Sherry, S. T.; McVean, G.; Durbin, R.; 1000 Genomes Project Analysis Group (2011)."The Variant Call Format and VCFtools".Bioinformatics.27 (15):2156–58.doi:10.1093/bioinformatics/btr330.PMC 3137218.PMID 21653522.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  23. ^Hernandez, R. D.; Kelley, J. L.; Elyashiv, E.; Melton, S. C.; Auton, A.; McVean, G.; 1000 Genomes Project; Sella, G.; Przeworski, M. (2011)."Classic Selective Sweeps Were Rare in Recent Human Evolution".Science.331 (6019):920–24.Bibcode:2011Sci...331..920H.doi:10.1126/science.1198878.PMC 3669691.PMID 21330547.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  24. ^"Gilean McVean".royalsociety.org. Retrieved30 December 2017.
  25. ^"Professor Cecilia Lindgren appointed Director of the Big Data Institute — Oxford Big Data Institute".www.bdi.ox.ac.uk. Retrieved29 April 2021.
  26. ^"AWARDS MADE IN 2006"(PDF).leverhulme.ac.uk. The Leverhulme Trust. 2006. Archived fromthe original(PDF) on 10 August 2016. Retrieved30 December 2017.
  27. ^"Philip Leverhulme Prizes 2006"(PDF).leverhulme.ac.uk. The Leverhulme Trust. 2006. Retrieved30 December 2017.
  28. ^The Royal Society (10 December 2013),Our genomes, our history,archived from the original on 15 December 2021, retrieved30 December 2017
  29. ^"Professor Gil McVean awarded the Weldon Memorial Prize 2012 - Wellcome Trust Centre for Human Genetics".well.ox.ac.uk. Retrieved30 December 2017.
  30. ^TEDx Talks (29 March 2013),A Thousand Genomes a Thousand Stories: Gilean McVean at TEDxWarwick 2013,archived from the original on 15 December 2021, retrieved30 December 2017
  31. ^"EMBO enlarges its membership for 50th anniversary".embo.org. Retrieved30 December 2017.
  32. ^Anon (2016)."Gilean McVean".royalsociety.org. London:Royal Society. Archived fromthe original on 29 April 2016.
  33. ^"New Fellows: Academy of Medical Sciences".acmedsci.ac.uk. Retrieved30 December 2017.
  34. ^"Professor Gil McVean elected a Fellow of the Royal Society - GENOMICS plc". Retrieved30 December 2017.
Fellows
Honorary
Foreign
International
Academics
People
Retrieved from "https://en.wikipedia.org/w/index.php?title=Gil_McVean&oldid=1321243341"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp