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| Trade names | Pressionorm, Wintonin |
| Other names | 3-Hydroxyamphetamine;meta-Hydroxyamphetamine; α-Methyl-meta-tyramine; 3-Hydroxy-α-methylphenethylamine |
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| ECHA InfoCard | 100.012.779 |
| Chemical and physical data | |
| Formula | C9H13NO |
| Molar mass | 151.209 g·mol−1 |
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Gepefrine, also known as3-hydroxyamphetamine orα-methyl-meta-tyramine and sold under the brand namesPressionorm andWintonin, is asympathomimeticmedication used as anantihypotensive agent which has been marketed inGermany.[1][2][3][4]
Gepefrine is described as asympathomimetic andantihypotensive agent.[5]
Gepefrine, also known as 3-hydroxy-α-methylphenethylamine or as 3-hydroxyamphetamine, is asubstituted phenethylamine andamphetaminederivative.[5] It is usedpharmaceutically as the (S)-enantiomer and as thetartratesalt.[5][1] Related compounds includemeta-tyramine (3-hydroxyphenethylamine),4-hydroxyamphetamine (norpholedrine),3,4-dihydroxyamphetamine (α-methyldopamine), andmetaraminol ((1R,2S)-3,β-dihydroxyamphetamine), among others.
Gepefrine wassynthesized by 1968[5] and was introduced for medical use inGermany by 1981.[3]
Gepefrine is thegeneric name of the drug and itsINNTooltip International Nonproprietary Name.[5] Brand names of gepefrine includePressionorm andWintonin.[1][6]
Gepefrine is a knownmetabolite ofamphetamine in rats.[4]
