| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Mouse |
| Target | CD147 |
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Gavilimomab (also known asABX-CBL) is amousemonoclonal antibody intended for use as an immunosuppressivebiologic treatment ofglucocorticoid-resistantgraft versus host disease. It binds to the antigenCD147.[1] Gavilimomab proved slightly less effective than standardantithymocyte globulin therapy.[2]
It was originally developed byAbgenix,[1] which was later acquired byAmgen.
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