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LPAR4

From Wikipedia, the free encyclopedia
(Redirected fromGPR23)
Protein-coding gene in the species Homo sapiens
LPAR4
Identifiers
AliasesLPAR4, GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9, lysophosphatidic acid receptor 4
External IDsOMIM:300086;MGI:1925384;HomoloGene:3871;GeneCards:LPAR4;OMA:LPAR4 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for LPAR4
Genomic location for LPAR4
BandXq21.1Start78,747,709bp[1]
End78,758,714bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for LPAR4
Genomic location for LPAR4
BandX|X DStart105,964,231bp[2]
End105,977,506bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • buccal mucosa cell

  • tibia

  • testicle

  • gonad

  • ventricular zone

  • cartilage tissue

  • ganglionic eminence

  • muscle of thigh

  • Achilles tendon
Top expressed in
  • dermis

  • pituitary stalk

  • efferent ductule

  • human fetus

  • primitive streak

  • trigeminal ganglion

  • tongue

  • Gonadal ridge

  • mandibular prominence

  • left lung lobe
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

2846

78134

Ensembl

ENSG00000147145

ENSMUSG00000049929

UniProt

Q99677

Q8BLG2

RefSeq (mRNA)

NM_001278000
NM_005296

NM_175271

RefSeq (protein)

NP_001264929
NP_005287

NP_780480

Location (UCSC)Chr X: 78.75 – 78.76 MbChr X: 105.96 – 105.98 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Lysophosphatidic acid receptor 4 also known asLPA4 is aprotein that in humans is encoded by theLPAR4gene.[5][6][7] LPA4 is aG protein-coupled receptor that binds the lipid signaling moleculelysophosphatidic acid (LPA).[8]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000147145Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000049929Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^"Entrez Gene: GPR23 G protein-coupled receptor 23".
  6. ^Janssens R, Boeynaems JM, Godart M, Communi D (July 1997). "Cloning of a human heptahelical receptor closely related to the P2Y5 receptor".Biochem. Biophys. Res. Commun.236 (1):106–12.doi:10.1006/bbrc.1997.6895.PMID 9223435.
  7. ^O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF, Lynch KR, George SR (March 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes".Gene.187 (1):75–81.doi:10.1016/S0378-1119(96)00722-6.PMID 9073069.
  8. ^Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin ME, Teo ST, Park KE, Mosley AN, Chun J (January 2010). "LPA Receptors: Subtypes and Biological Actions".Annual Review of Pharmacology and Toxicology.50 (1):157–186.doi:10.1146/annurev.pharmtox.010909.105753.PMID 20055701.

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

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