Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

GJD3

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
GJD3
Identifiers
AliasesGJD3, CX31.9, Cx30.2, GJA11, GJC1, gap junction protein delta 3
External IDsOMIM:607425;MGI:2384150;HomoloGene:17530;GeneCards:GJD3;OMA:GJD3 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for GJD3
Genomic location for GJD3
Band17q21.2Start40,360,652bp[1]
End40,364,737bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for GJD3
Genomic location for GJD3
Band11|11 DStart98,873,006bp[2]
End98,873,842bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad

  • apex of heart

  • spleen

  • mucosa of ileum

  • stromal cell of endometrium

  • left ventricle

  • right lung

  • gallbladder

  • mucosa of transverse colon

  • smooth muscle tissue
Top expressed in
  • spermatocyte

  • embryo

  • spermatid

  • embryo

  • primary visual cortex

  • testicle

  • Cortex of frontal lobe

  • superior frontal gyrus

  • neural tube

  • striatum of neuraxis
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

125111

353155

Ensembl

ENSG00000183153

ENSMUSG00000047197

UniProt

Q8N144

Q91YD1

RefSeq (mRNA)

NM_152219

NM_178596

RefSeq (protein)

NP_689343

NP_848711

Location (UCSC)Chr 17: 40.36 – 40.36 MbChr 11: 98.87 – 98.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gap junction delta-2 (GJD2), also known asconnexin-36 (Cx36) orgap junction alpha-9 (GJA9), is aprotein that in humans is encoded by theGJD2gene.[5]

Function

[edit]

This gene is a member of the large family ofconnexins that are required for the formation ofgap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, thus forming a channel linking the cytoplasm of the 2 cells.[5]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000183153Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000047197Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: gap junction protein".

Further reading

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

Ligand-gated
Voltage-gated
Constitutively active
Proton-gated
Voltage-gated
Calcium-activated
Inward-rectifier
Tandem pore domain
Voltage-gated
Miscellaneous
Cl:Chloride channel
H+:Proton channel
M+:CNG cation channel
M+:TRP cation channel
H2O (+solutes):Porin
Cytoplasm:Gap junction
By gating mechanism
Ion channel class
see alsodisorders


Stub icon

This article on agene on humanchromosome 17 is astub. You can help Wikipedia byadding missing information.

Retrieved from "https://en.wikipedia.org/w/index.php?title=GJD3&oldid=1300571478"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2026 Movatter.jp