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G-5 (drug)

From Wikipedia, the free encyclopedia
This article is about the psychedelic drug. For other uses, seeG5.
Pharmaceutical compound
G-5
Clinical data
Other namesG5; Ganesha-5; GANESHA-5; 3C-G-5; 3,4-Norbornyl-2,5-dimethoxyamphetamine; 3,6-Dimethoxy-4-(2-aminopropyl)benzonorbornane; DOG-5
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic;Hallucinogen
ATC code
  • None
Pharmacokinetic data
Onset of actionVery slow[1]
Duration of action16–30 hours[1]
Identifiers
  • 1-(3,6-dimethoxy-4-tricyclo[6.2.1.02,7]undeca-2,4,6-trienyl)propan-2-amine
CAS Number
PubChemCID
ChemSpider
Chemical and physical data
FormulaC16H23NO2
Molar mass261.365 g·mol−1
3D model (JSmol)
  • CC(CC1=CC(=C2C3CCC(C3)C2=C1OC)OC)N
  • InChI=1S/C16H23NO2/c1-9(17)6-12-8-13(18-2)14-10-4-5-11(7-10)15(14)16(12)19-3/h8-11H,4-7,17H2,1-3H3
  • Key:MZFVFTFFHRCTIO-UHFFFAOYSA-N

G-5, also known as3,4-norbornyl-2,5-dimethoxyamphetamine, is apsychedelic drug of thephenethylamine,amphetamine, andDOx families.[1][2][3] It is one of severalhomologues ofGanesha (G).[1][2][3]

In his bookPiHKAL (Phenethylamines I Have Known and Loved) and other publications,Alexander Shulgin lists G-5's dose as 14 to 20 mgorally and itsduration as 16 to 30 hours.[1][2][3] It is said to have a very slowonset.[1] The effects of G-5 were reported to include an unexpected absence ofvisual and relatedsensory activity, excellent mental activity, "absence of the bells and whistles that are expected with a psychedelic in full bloom", mental integration, and little or nobody load.[1] Per Shulgin, it was somehow lacking in characteristics that would've made it fully favorable, perhaps the lack of perceptual effects, which resulted in there being little drive to further explore it.[1]

The drug is not amonoamine releasing agent of eitherserotonin ordopamine.[4] Thechemical synthesis of G-5 has been described.[1]

G-5 was first described in the literature by Shulgin and colleagues in 1991.[1][4] It is acontrolled substance inCanada under phenethylamine blanket-ban language.[5]

See also

[edit]

References

[edit]
  1. ^abcdefghijkShulgin, Alexander;Shulgin, Ann (September 1991).PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.https://erowid.org/library/books_online/pihkal/pihkal084.shtml
  2. ^abcJacob P, Shulgin AT (1994)."Structure-Activity Relationships of the Classic Hallucinogens and Their Analogs". In Lin GC, Glennon RA (eds.).Hallucinogens: An Update(PDF). National Institute on Drug Abuse Research Monograph Series. Vol. 146. National Institute on Drug Abuse. pp. 74–91.PMID 8742795. Archived fromthe original on 13 July 2025.
  3. ^abcShulgin AT (2003)."Basic Pharmacology and Effects". In Laing RR (ed.).Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137.ISBN 978-0-12-433951-4. Archived fromthe original on 13 July 2025.
  4. ^abMcKenna DJ, Guan XM, Shulgin AT (March 1991). "3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine".Pharmacol Biochem Behav.38 (3):505–512.doi:10.1016/0091-3057(91)90005-m.PMID 1829838.
  5. ^"Controlled Drugs and Substances Act".Department of Justice Canada. Retrieved19 January 2026.

External links

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