In the early Middle Ages the tiny county ofBurgau ruled the region. In 1213 the county was acquired by the lords ofBerg; it was then known as Berg-Burgau, but the last ruler of this collateral line died in 1301, andBurgau (now raised to the level of amargraviate) became an exclave ofAustria. In the early 17th century the administrative seat was moved from the town of Burgau to Günzburg, but themargraviate retained its name. When theHoly Roman Empire ceased to exist in 1806, themargraviate was dissolved and the region was annexed byBavaria.
The district was established in 1972 by merging the former districts of Günzburg andKrumbach.Günzburg lost its status as anurban district and became the administrative seat of the new district.
TheDanube river and its tributaries characterise this district. The Danube runs through the northernmost parts of the district, passing the cities of Günzburg and Leipheim. There are several affluents coming from the south, for exampleBiber,Günz andMindel. Most of the district's area is covered with forests; the eastern third of the territory is part of theAugsburg Western Forests Nature Park.
On the right there are the old arms of the margravate of Burgau: red and white with a yellow beam. The eagle is from the arms of the Schwabegg-Ursberg family, which founded two monasteries in the district.