Functio laesa is a term used in medicine to refer to a loss of function[1][2] or a disturbance of function.[3]
It was identified as the fifth sign of acuteinflammation byGalen, who added it to the four signs identified byCelsus (tumor,rubor,calor, anddolor).[4]
The attribution to Galen is disputed,[3] and has variously been attributed toThomas Sydenham[5] andRudolf Virchow.[6]