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Functio laesa

From Wikipedia, the free encyclopedia
Loss of organ function

Functio laesa is a term used in medicine to refer to a loss of function[1][2] or a disturbance of function.[3]

It was identified as the fifth sign of acuteinflammation byGalen, who added it to the four signs identified byCelsus (tumor,rubor,calor, anddolor).[4]

The attribution to Galen is disputed,[3] and has variously been attributed toThomas Sydenham[5] andRudolf Virchow.[6]

References

[edit]
  1. ^"Dorlands Medical Dictionary:cardinal signs".
  2. ^"Definition: functio laesa from Online Medical Dictionary".
  3. ^abRather LJ (March 1971)."Disturbance of function (functio laesa): The legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus".Bull N Y Acad Med.47 (3):303–22.PMC 1749862.PMID 5276838.
  4. ^Porth, Carol (2007).Essentials of pahtophysiology: concepts of altered health states. Hagerstown, MD: Lippincott Williams & Wilkins. p. 270.ISBN 978-0-7817-7087-3.
  5. ^Dormandy, Thomas (2006).The worst of evils: man's fight against pain. New Haven, Conn: Yale University Press. pp. 22.ISBN 0-300-11322-6.
  6. ^David Lowell Strayer; Raphael Rubin (2007).Rubin's Pathology: Clinicopathologic Foundations of Medicine 5th Edition. Hagerstown, MD: Lippincott Williams & Wilkins. p. 37.ISBN 978-0-7817-9516-6.
Symptoms
Mechanism
Acute
Plasma-derived mediators
Cell-derived mediators
preformed
synthesized on demand
Chronic
Other
Tests
General


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