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| Clinical data | |
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| Other names | 4-Isothiocyanato-PCP |
| Drug class | Irreversibledopamine transporter blocker;ReversibleNMDA receptor antagonist;Psychostimulantantagonist |
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| Chemical and physical data | |
| Formula | C18H24N2S |
| Molar mass | 300.46 g·mol−1 |
| 3D model (JSmol) | |
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Fourphit, also known as4-isothiocyanato-PCP, is anirreversibledopamine transporter (DAT)blocker and a reversibleNMDA receptor antagonist.[1][2] It blocks the binding ofmethylphenidate to the DATin vitro,[1] though apparently notin vivo.[2] In any case, the drug reduces thestimulant-like effects ofcocaine in animals,[2] whilst producing mostly negligible behavioral effects itself.[2] Fourphit is anacylatingderivative ofphencyclidine (PCP) and apositional isomer ofmetaphit (3-isothiocyanato-PCP).[1]
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