Finegoldia is a genus ofGram-positive bacteria. They areanaerobiccocci of the classClostridia, withFinegoldia magna being thetype species.[1]F. magna was formerly known, along with several other Gram-positive anaerobic cocci (GPACs), asPeptostreptococcus magnus, but was moved into its own genus in 1999.[2][3] The name is in honor ofSydney M. Finegold, an Americanmicrobiologist, whilemagna isLatin for large.[1] It is anopportunistic humanpathogen that normally colonizes skin andmucous membranes.[4] It is often seen inbiofilms on chronic ulcers such as in diabetic foot ordecubitus ulcers.[3] Most surveys have found it to be susceptible topenicillins,carbapenems andmetronidazole, though resistant strains have been identified.[5] Resistance toclindamycin is common and has been seen in over 10% of isolates in the US.[3][6] One review stated that "the combination of diminished antimicrobial susceptibility, its prevalence, and the described virulence factors givesF. magna a special position among the GPAC."[5]
^Murdoch, D. A; Shah, H. N (1999-10-01). "Reclassification of Peptostreptococcus magnus (Prevot 1933) Holdeman and Moore 1972 as Finegoldia magna comb. nov. and Peptostreptococcus micros (Prevot 1933) Smith 1957 as Micromonas micros comb. nov".Anaerobe.5 (5):555–559.doi:10.1006/anae.1999.0197.
^abcJohn e. Bennett, MD; Raphael Dolin, MD; Martin j. Blaser, MD (2014-08-28). "Anaerobic Cocci and Anaerobic Gram-Positive Nonsporulating Bacilli".Mandell, Douglas, and Bennett's principles and practice of infectious diseases.ISBN978-1-4557-4801-3.
^de Moreuil, Claire; Héry-Arnaud, Geneviève; David, Charles-Henri; Provost, Bastien; Mondine, Philippe; Alavi, Zarrin; de Saint Martin, Luc; Bezon, Eric; Berre, Rozenn Le (2015-04-01). "Finegoldia magna, not a well-known infectious agent of bacteriemic post-sternotomy mediastinitis".Anaerobe.32:32–33.doi:10.1016/j.anaerobe.2014.11.012.PMID25448620.
