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Sodium ferric gluconate complex

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(Redirected fromFerrlecit)

Pharmaceutical compound
Sodium ferric gluconate complex
Clinical data
Trade namesFerrlecit
AHFS/Drugs.comMonograph
MedlinePlusa614030
License data
Routes of
administration
Intravenous (IV)
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC66H121Fe2NaO65
Molar mass2089.309 g·mol−1
3D model (JSmol)
  • O[C@H]([C@@H](O)C(O[Na])=O)[C@H](O)[C@H](O)CO.O[C@H]([C@@H](O)C(O1)=O)[C@H](O)[C@H](O)CO.[Fe]1(OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
  • InChI=1S/5C12H22O11.C6H12O7.2Fe.Na.3O/c5*13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;/h5*4-11,13-20H,1-3H2;2-5,7-11H,1H2,(H,12,13);;;;;;/q;;;;;;2*+3;+1;3*-2/p-1/t5*4-,5-,6-,7-,8+,9-,10+,11-,12+;2-,3-,4+,5-;;;;;;/m111111....../s1
  • Key:MQBDAEHWGRMADS-XNHLMZCASA-M

Sodium ferric gluconate complex, sold under the brand nameFerrlecit, is an intravenously administered iron medication for the treatment ofiron deficiency anemia in adults and in children aged six years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy.[2] The macromolecule has an apparent molecular weight of 289,000–440,000 Dalton.[3][4]

The most commonside effects in adults are nausea, vomiting and/or diarrhea,injection site reaction, hypotension, cramps, hypertension, dizziness, dyspnea, chest pain, leg cramps, and pain.[2] In children the most commonside effects are hypotension, headache, hypertension, tachycardia and vomiting.[2]

References

[edit]
  1. ^"Sodium ferric gluconate complex Use During Pregnancy".Drugs.com. 16 December 2019. Retrieved2 April 2020.
  2. ^abc"Ferrlecit- sodium ferric gluconate complex injection".DailyMed. 25 September 2019. Retrieved2 April 2020.
  3. ^"Sodium ferric gluconate complex".www.drugbank.ca. Retrieved21 June 2020.[title missing]
  4. ^Fishbane S, Wagner J (May 2001). "Sodium ferric gluconate complex in the treatment of iron deficiency for patients on dialysis".American Journal of Kidney Diseases.37 (5):879–83.doi:10.1016/s0272-6386(05)80001-0.PMID 11325667.
Erythropoietins
Iron supplements
Vitamin B12 and
folic acid supplements
HIF prolyl-hydroxylase inhibitors
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