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Felbinac

From Wikipedia, the free encyclopedia
Topical NSAID medication
Pharmaceutical compound
Felbinac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Topical
ATC code
Legal status
Legal status
Identifiers
  • biphenyl-4-ylacetic acid
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.024.758Edit this at Wikidata
Chemical and physical data
FormulaC14H12O2
Molar mass212.248 g·mol−1
3D model (JSmol)
  • O=C(O)Cc1ccc(cc1)c2ccccc2
  • InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) checkY
  • Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N checkY
  (verify)

Felbinac (INN, orbiphenylylacetic acid) is atopical medicine,[1] belonging to the family of medicines known asnonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation andarthritis.[2] It is an active metabolite offenbufen.[3]

Related compounds

[edit]

The α-methyl acid of felbinac is calledbiprofen and is used to preparebifepramide. The α-ethyl acid is calledxenbucin which is used to makexenthiorate.

See also

[edit]

References

[edit]
  1. ^The Merck Index, 12th Edition. 3989
  2. ^Description of Felbinac on Tiscali[1]
  3. ^Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function".Arzneimittelforschung.30 (4A):702–707.PMID 6254545.
pyrazolones /
pyrazolidines
salicylates
acetic acid derivatives
and related substances
oxicams
propionic acid
derivatives (profens)
n-arylanthranilic
acids (fenamates)
COX-2 inhibitors
(coxibs)
other
NSAID
combinations
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;withdrawn drugs;veterinary use.
Topical products forjoint andmuscular pain (M02)
Anti-inflammatory
preparations,
non-steroids
Pyrazolidines
Acetic acid
derivatives
Other
Capsaicin derivatives
Other
Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(
PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthase
PGFSTooltip Prostaglandin F synthase
PGI2STooltip Prostacyclin synthase
TXASTooltip Thromboxane A synthase
Others


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