| Facial motor nucleus | |
|---|---|
 Plan of the facial and intermediate nerves and their communication with other nerves. ("Nucleus of Facial N." labeled at upper left.) | |
 Diagram of brain stem showing the nuclei of the cranial nerves | |
| Details | |
| Part of | Medulla oblongata |
| Artery | AICA |
| Vein | Anterior medullary |
| Identifiers | |
| Latin | Nucleus nervi facialis |
| MeSH | D065828 |
| NeuroNames | 586 |
| NeuroLex ID | birnlex_903 |
| TA98 | A14.1.05.412 |
| TA2 | 5939 |
| FMA | 54572 |
| Anatomical terms of neuroanatomy | |
Thefacial motor nucleus is acollection of neurons in thebrainstem that belong to thefacial nerve (cranial nerve VII).[1] Theselower motor neurons innervate themuscles of facial expression and thestapedius.[2]
Thenucleus is situated in the caudal portion of the ventrolateralpontine tegmentum. Its axons take an unusual course, traveling dorsally and looping around theabducens nucleus, then traveling ventrally to exit theventral pons medial to thespinal trigeminal nucleus. These axons form the motor component of thefacial nerve, withparasympathetic andsensory components forming theintermediate nerve.
The nucleus has a dorsal and ventral region, with neurons in the dorsal region innervating muscles of the upper face and neurons in the ventral region innervating muscles of the lower face.
Because it innervates muscles derived frompharyngeal arches, the facial motor nucleus is considered part of thespecial visceral efferent (SVE) cell column, which also includes thetrigeminal motor nucleus,nucleus ambiguus, and (arguably) thespinal accessory nucleus.
Like all lower motor neurons, cells of the facial motor nucleus receivecortical input from theprimary motor cortex in thefrontal lobe of thebrain.Upper motor neurons of the cortex send axons that descend through theinternal capsule and synapse on neurons in the facial motor nucleus. This pathway from the cortex to the brainstem is called thecorticobulbar tract.
The neurons in the dorsal aspect of the facial motor nucleus receive inputs from both sides of the cortex, while those in the ventral aspect mainly receive contralateral inputs (i.e. from the opposite side of the cortex). The result is that both sides of the brain control the muscles of the upper face, while the right side of the brain controls the lower left side of the face, and the left side of the brain controls the lower right side of the face.
As a result of the corticobulbar input to the facial motor nucleus, an upper motor neuron lesion to fibers innervating the facial motor nucleus results incentral seven. The syndrome is characterized by spastic paralysis of the contralateral lower face. For example, a left corticobulbar lesion results in paralysis of the muscles that control the lower right quadrant of the face.
By contrast, a lower motor neuron lesion to the facial motor nucleus results inparalysis of facial muscles on the same side of the injury. If a cause, such as trauma or infection, cannot be identified (this situation is calledidiopathic palsy) this condition is known asBell's palsy. Otherwise it is described by its cause.
Any lesion occurring within or affecting the corticobulbar tract is known as an upper motor neuron lesion. Any lesion affecting the individual branches (temporal, zygomatic, buccal, mandibular and cervical) is known as a lower motor neuron lesion.
Branches of the facial nerve leaving the facial motor nucleus (FMN) for the muscles do so via both left and right posterior (dorsal) and anterior (ventral) routes. In other words, this means lower motor neurons of the facial nerve can leave either from the left anterior, left posterior, right anterior or right posterior facial motor nucleus. The temporal branch travels out from the left and right posterior components. The inferior four branches do so via the left and right anterior components. The left and right branches supply their respective sides of the face (ipsilateral innervation). Accordingly, the posterior components receive motor input from both hemispheres of the cerebral cortex (bilaterally), whereas the anterior components receive strictly contralateral input. This means that the temporal branch of the facial nerve receives motor input from both hemispheres of the cerebral cortex whereas the zygomatic, buccal, mandibular and cervical branches receive information from only contralateral hemispheres.
Now, because the anterior FMN receives only contralateral cortical input whereas the posterior receives that which is bilateral, a corticobulbar lesion (UMN lesion) occurring in the left hemisphere would eliminate motor input to the right anterior FMN component, thus removing signaling to the inferior four facial nerve branches, thereby paralyzing the right mid- and lower-face. The posterior component, however, although now only receiving input from the right hemisphere, is still able to allow the temporal branch to sufficiently innervate the entire forehead. This means that the forehead will not be paralyzed.
The same mechanism applies for an upper motor neuron lesion in the right hemisphere. The left anterior FMN component no longer receives cortical motor input due to its strict contralateral innervation, whereas the posterior component is still sufficiently supplied by the left hemisphere. The result is paralysis of the left mid- and lower-face with an unaffected forehead.
On the other hand, a lower motor neuron lesion is a bit different.
A lesion on either the left or right side would affect both the anterior and posterior routes on that side because of their close physical proximity to one another. So, a lesion on the left side would inhibit muscle innervation from both the left posterior and anterior routes, thus paralyzing the whole left side of the face (Bell’s palsy). With this type of lesion, the bilateral and contralateral inputs of the posterior and anterior routes, respectively, become irrelevant because the lesion is below the level of the medulla and the facial motor nucleus. Whereas at a level above the medulla a lesion occurring in one hemisphere would mean that the other hemisphere could still sufficiently innervate the posterior facial motor nucleus, a lesion affecting a lower motor neuron would eliminate innervation altogether because the nerves no longer have a means to receive compensatory contralateral input at a downstream decussation.
Thus, the main distinction between an UMN and LMN lesion is that in the former, there is hemiplegia of the contralateral mid- and lower-face, whereas in the latter, there is complete hemiplegia of the ipsilateral face.
