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FP-β-CPPIT

From Wikipedia, the free encyclopedia
Cocaine analogue
Pharmaceutical compound
FP-β-CPPIT
Clinical data
Other namesN-(3'-Fluoropropyl)-3β-(4'-chlorophenyl)-2β-(3'-phenylisoxazol-5'-yl)nortropane
Identifiers
  • (1R,2S,3S,5S)-3-(4-chlorophenyl)-8-(3-fluoropropyl)-2-(3-phenylisoxazol-5-yl)-8-azabicyclo[3.2.1]octane
PubChemCID
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC25H26ClFN2O
Molar mass424.94 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1)[C@H]5C[C@@H]2CC[C@@H](N2CCCF)[C@H]5c3cc(no3)c4ccccc4
  • InChI=1S/C25H26ClFN2O/c26-19-9-7-17(8-10-19)21-15-20-11-12-23(29(20)14-4-13-27)25(21)24-16-22(28-30-24)18-5-2-1-3-6-18/h1-3,5-10,16,20-21,23,25H,4,11-15H2/t20-,21+,23+,25-/m0/s1
  • Key:PEFGYCYPBHWUJP-JIEYXDDVSA-N

N-(3'-Fluoropropyl-)-3β-(4'-chlorophenyl)-2β-(3'-phenylisoxazol-5'-yl)nortropane (FP-β-CPPIT) is acocaineanalogue.[1]

See also

[edit]

References

[edit]
  1. ^Schönbächler RD (1999).Evaluation of Three Cocaine Analogues as PET tracers for the Dopamine Transporter and Synthetic Approaches to [F-18]-DFMO(PDF) (Diss. Naturwiss. thesis). Vol. 13287. ETH Zürich.doi:10.3929/ethz-a-003824386.hdl:20.500.11850/144279. Retrieved2012-08-22.
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DATTooltip Dopamine transporter
(DRIsTooltip Dopamine reuptake inhibitors)
NETTooltip Norepinephrine transporter
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2-Carboxymethyl Esters
(3,4-Disubstituted Phenyl)-tropanes
Arylcarboxy
Carboxyalkyl
Acyl
β,α Stereochemistry
α,β Stereochemistry
Heterocycles: 3-Substituted-isoxazol-5-yl
Heterocycles: 3-Substituted-1,2,4-oxadiazole
N-alkyl
N-replaced (S,O,C)
Irreversible
Nortropanes (N-demethylated)


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