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F-2 (drug)

From Wikipedia, the free encyclopedia
Psychedelic drug
Pharmaceutical compound
F2
Clinical data
ATC code
  • None
Legal status
Legal status
Identifiers
  • 1-(5-methoxy-2-methyl-2,3-dihydro-1-benzofuran-6-yl)propan-2-amine
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC13H19NO2
Molar mass221.300 g·mol−1
3D model (JSmol)
  • C1=C2C(=CC(=C1CC(C)N)OC)CC(O2)C
  • InChI=1S/C13H19NO2/c1-8(14)4-10-7-13-11(5-9(2)16-13)6-12(10)15-3/h6-9H,4-5,14H2,1-3H3 checkY
  • Key:XBHKBTCXRYPZMX-UHFFFAOYSA-N checkY
  (verify)

F-2, also known as6-(2-aminopropyl)-5-methoxy-2-methyl-2,3-dihydrobenzofuran or asbenzofuran-2-methyl-5-methoxy-6-(2-aminopropane), is a lesser-knownpsychedelic drug. F-2 was first synthesized byAlexander Shulgin. In his bookPiHKAL, the minimum dosage is listed as 15 mg, and its duration is unknown.[1] F-2 produces few to no effects at this dose in humans. Animal studies showed it to substitute for the psychedelic drugDOM, but with less than one tenth the potency.[2] F-2 is thederivative of6-APDB with amethyl group at thecarbonatom of the 3,4-methylenedioxy ring and amethoxy group at the 6 position.

Society and culture

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Legal status

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United Kingdom

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This substance is a Class A drug in theDrugs controlled by the UK Misuse of Drugs Act.[3]

See also

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References

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  1. ^Shulgin A,Shulgin A (September 1991).PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.F-2 Entry inPiHKAL
  2. ^Nichols DE, Hoffman AJ, Oberlender RA, Riggs RM (February 1986). "Synthesis and evaluation of 2,3-dihydrobenzofuran analogues of the hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane: drug discrimination studies in rats".Journal of Medicinal Chemistry.29 (2):302–4.doi:10.1021/jm00152a022.PMID 3950910.
  3. ^"UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Archived fromthe original on 22 October 2017. Retrieved12 March 2014.
Tryptamines
No ring subs.
4-Hydroxytryptamines
5-Hydroxytryptamines
5-Methoxytryptamines
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