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3D model (JSmol) | |
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| C6H14ClNO | |
| Molar mass | 151.63 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Ethylcholine mustard is a neurotoxicnitrogen mustard that destroyscholinergic neurons.[2][3] It's the hydrolysis product of theHN1vesicant.[1]
Under aqueous condition, ethylcholine mustard forms the highly reactive ethylcholine aziridinium (AF64A) ion. AF64A is transported into cholinergic neurons by thecholine transporter. AF64A irreversibly inhibits thecholine acetyltransferase and thereby inhibitsacetylcholine synthesis. AF64A can also produce cytotoxic effects, leading to cell death.[2][3]
The aziridinium ion can be isolated aspicrylsulfonate salt.[1]
 | Thisneurotoxin article is astub. You can help Wikipedia byadding missing information. |
