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| Formula | C14H18ClNO |
| Molar mass | 251.75 g·mol−1 |
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N-Ethylnorketamine (ethketamine,NENK,2-Cl-2'-Oxo-PCE) is adesigner drug which is presumed to have similar properties toketamine, adissociativeanesthetic drug withhallucinogenic andsedative effects. It has been sold over the internet since around September 2012, and identified in seized drug samples by analytical laboratories in the UK and other European countries.[1]
It is anNMDA receptor antagonist. In mice its antidepressant effects are dependent on activation ofAMPA and5-HT2 receptors, as blocking those abolishes said activity.[2]
As of October 2015 NENK is a controlled substance in the United Kingdom,[3] China,[4] and the US state of Alabama.[5]
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