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Esophageal motility disorder

From Wikipedia, the free encyclopedia
Inability to coordinate movement of the esophagus
Medical condition
Esophageal motility disorder
Other namesEsophageal dysmotility (ED)
Diagnostic methodEsophageal motility study
Functional Lumen Imaging Probe
Treatmenttreatment depends on cause

Anesophageal motility disorder (EMD) is anymedical disorder resulting from dysfunction of the coordinated movement of esophagus, which causesdysphagia (i.e. difficulty inswallowing,regurgitation of food).[1]

Primary motility disorders are:[1]

An esophageal motility disorder can also be secondary to other diseases.[1] For example, it may be a result ofCREST syndrome, referring to the five main features:calcinosis,Raynaud syndrome, esophageal dysmotility,sclerodactyly andtelangiectasia.[2]

Symptoms

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The most common symptom of esophageal motility disorders isdysphagia. Compared to causes of mechanical obstruction, which usually coincide with difficulties only with solids, dysphagia occurs in both solid foods and liquids.Heartburn,odynophagia,chest pain, anddyspnea are frequent symptoms of esophageal motility disorders, as they are in otheresophageal disorders. Advancedachalasia is characterized byregurgitation of previously swallowed, undigested food material. Individuals withdiffuse esophageal spasm ornutcracker esophagus, due to disorderedperistalsis propagation, may experience severe chest pain and dysphagia, mimickingcardiac ischemia.[3]

Achalasia's most common symptoms include dysphagia (difficulty swallowing solids and liquids), regurgitation of undigested food, respiratory issues (aspiration and nocturnalcough), chest pain, andweight loss.[4]

Diffuse esophageal spasm (DES) is a motility disorder characterized by recurrent episodes of chest pain or dysphagia as well as nonpropulsive (tertiary) contractions onradiographs.[5]

Nutcracker esophagus is characterized by high-amplitude peristaltic contractions that are frequently prolonged and cause dysphagia and chest pain.[6]

HLES (hypertensive lower esophageal sphincter) is a rare manometric abnormality seen among individuals with dysphagia, chest pain,gastroesophageal reflux, andhiatal hernia.[7]

Diagnosis

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Testing to diagnose EMD includesbarium esophagography,upper endoscopy, andesophageal manometry.[8]

Treatment

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There is no cure for EMD, but symptoms can be managed. Some symptom management includes eating slower and taking smaller bites; in some cases medications can be useful to manage other issues that contribute to EMD such as aproton pump inhibitor to easegastroesophageal reflux (acid reflux), or a smooth muscle relaxant for issues with the muscles.[8]

See also

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  • Functional Lumen Imaging Probe
  • References

    [edit]
    1. ^abcGoyal, Manjeet; Nagalli, Shivaraj (2023),"Esophageal Motility Disorders",StatPearls, Treasure Island (FL): StatPearls Publishing,PMID 32965826, retrieved2023-10-20
    2. ^Winterbauer RH (1964). "Multiple telangiectasia, Raynaud's phenomenon, sclerodactyly, and subcutaneous calcinosis: a syndrome mimicking hereditary hemorrhagic telangiectasia".Bulletin of the Johns Hopkins Hospital.114:31–83.PMID 14171636.
    3. ^Guth, Todd A. (2013)."Esophageal Disorders".Emergency Medicine. Elsevier. pp. 269–278.e1.doi:10.1016/b978-1-4377-3548-2.00031-8.ISBN 978-1-4377-3548-2. RetrievedNovember 18, 2023.
    4. ^Boeckxstaens, G.E.E. (2007)."Achalasia".Best Practice & Research Clinical Gastroenterology.21 (4). Elsevier BV:595–608.doi:10.1016/j.bpg.2007.03.004.ISSN 1521-6918. RetrievedNovember 18, 2023.
    5. ^Almansa, Cristina; Hinder, Ronald A.; Smith, C. Daniel; Achem, Sami R. (December 11, 2007)."A Comprehensive Appraisal of the Surgical Treatment of Diffuse Esophageal Spasm".Journal of Gastrointestinal Surgery.12 (6). Springer Science and Business Media LLC:1133–1145.doi:10.1007/s11605-007-0439-x.ISSN 1091-255X.PMID 18071832.S2CID 20620057. RetrievedNovember 18, 2023.
    6. ^Horton, Marshall L.; Goff, John S. (1986)."Surgical treatment of nutcracker esophagus".Digestive Diseases and Sciences.31 (8). Springer Science and Business Media LLC:878–883.doi:10.1007/bf01296058.ISSN 0163-2116.PMID 3731979.S2CID 24020786. RetrievedNovember 18, 2023.
    7. ^Gad El-Hak, NabilA; Mostafa, Mohamed; AbdelHamid, Hussein; Haleem, Magdy (2006)."Hypertensive lower esophageal sphincter (HLES): Prevalence,symptoms genesis and effect of pneumatic balloon dilatation".Saudi Journal of Gastroenterology.12 (2). Medknow:77–82.doi:10.4103/1319-3767.27850.ISSN 1319-3767.PMID 19858590. RetrievedNovember 18, 2023.
    8. ^abMcQuaid, Kenneth (2022).Current Medical Diagnosis & Treatment 2022. McGraw Hill.

    External links

    [edit]
    Classification
    External resources
    Diseases of thehuman digestive system
    Upper GI tract
    Esophagus
    Stomach
    Lower GI tract
    Enteropathy
    Small intestine
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    Large and/or small
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    GI bleeding
    Accessory
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    Bile duct/
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