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| Names | |
|---|---|
| IUPAC names [(2R,3R)-2,3-Dihydroxy-4-oxobutyl] phosphate d-Erythrose 4-(dihydrogen phosphate) | |
| Other names E4P | |
| Identifiers | |
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3D model (JSmol) | |
| ChEBI | |
| ChemSpider |
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| MeSH | erythrose+4-phosphate |
| UNII | |
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| Properties | |
| C4H9O7P | |
| Molar mass | 200.084 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Erythrose 4-phosphate is aphosphate of the simple sugarerythrose. It is an intermediate in thepentose phosphate pathway and theCalvin cycle.[1]
The enzymetransaldolase catalyzes the formation of erythrose 4-phosphate andfructose 6-phosphate fromsedoheptulose 7-phosphate andglyceraldehyde 3-phosphate.[2] This reaction is a part of the non-oxidative phase of the pentose phosphate pathway.
In the Calvin cycle, the enzymefructose-bisphosphate aldolase catalyzes the formation of sedoheptulose 1,7-bisphosphate from erythrose 4-phosphate anddihydroxyacetone phosphate.[3]
In addition, it serves as a precursor in the biosynthesis of the aromatic amino acidstyrosine,phenylalanine, andtryptophan. It is used in the first step of theshikimate pathway. At this stage,phosphoenolpyruvate and erythrose-4-phosphate react to form3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP), in a reaction catalyzed by the enzymeDAHP synthase.
It also used in3-hydroxy-1-aminoacetone phosphate biosynthesis, which is a precursor ofvitamin B6 inDXP-dependent pathway.Erythrose-4-phosphate dehydrogenase is used to produceerythronate-4-phosphate.
