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Erwin Neher

From Wikipedia, the free encyclopedia
German biophysicist and Nobel laureate
Erwin Neher
Erwin Neher in June 2015
Born (1944-03-20)20 March 1944 (age 81)
Alma mater
Known forpatch clamp
Awards
Scientific career
FieldsBiophysics[2][3][4]
Institutions
Academic advisorsCharles F. Stevens
Websitewww.mpg.de/323786/biophysikalische_chemie_wissM6

Erwin Neher (German pronunciation:[ˈɛʁviːnˈneːɐ];/ˈnər/;[5] born 20 March 1944) is a Germanbiophysicist, specializing in the field ofcell physiology. For significant contribution in the field, in 1991 he was awarded, along withBert Sakmann, theNobel Prize in Physiology or Medicine for "their discoveries concerning the function of singleion channels in cells".[6][7][8]

Early life and education

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Neher was born inLandsberg am Lech,Upper Bavaria, the son of Elisabeth (née Pfeiffer), a teacher, and Franz Xaver Neher, an executive at a dairy company.[9] He studied physics at theTechnical University of Munich from 1963 to 1966.

In 1966, he was awarded aFulbright Scholarship to study in the US. He spent a year at theUniversity of Wisconsin–Madison, and earned a master's degree in biophysics. While at the laboratory of theMax-Planck-Institute for Biophysical Chemistry he met fellow scientistEva-Maria Neher (born Ruhr), whom he married in 1978 and subsequently the couple had five children –Richard, Benjamin, Carola, Sigmund and Margret.[10]

In 2003 Neher was one of 22 Nobel Laureates who signed theHumanist Manifesto.[11]

Career

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In 1986, he was awarded theLouisa Gross Horwitz Prize fromColumbia University together withBert Sakmann. In 1987, he received theGottfried Wilhelm Leibniz Prize of theDeutsche Forschungsgemeinschaft, which is the highest honour awarded in German research. Along withBert Sakmann, he was awarded theNobel Prize in Physiology or Medicine in 1991 for "their discoveries concerning the function of singleion channels in cells".[12] Neher and Sakmann were the first to record the currents of single ion channels on a live cell (they were first recorded using the lipid bilayer method) through their development of thepatch-clamp technique,.[13][14][15][16] The methodology has been further developed with the strong encouragement of Charles F. Stevens in his laboratory atYale University.

Since 1983, he became a director at theMax Planck Institute for Biophysical Chemistry inGöttingen and led the Department for Membrane Biophysics. He turned into an emeritus director of the Institute since 2011. He is also a Professor Emeritus at theUniversity of Göttingen and used to be co-chair of theBernstein Center for Computational Neuroscience Göttingen.

Honors and awards

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Neher holds honorary degrees from:[17]

Neher was elected aForeign Member of the Royal Society (ForMemRS) in 1994.[1]

References

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  1. ^abc"Professor Erwin Neher ForMemRS". London:Royal Society. Archived fromthe original on 2015-10-11.
  2. ^Elektronische Messtechnik in der Physiologie. Berlin, New York, Springer-Verlag, 1974.
  3. ^Single-channel recording / edited by Bert Sakmann and Erwin Neher. New York: Plenum Press, c1983.ISBN 0-306-41419-8
  4. ^Single-Channel Recording / edited by Bert Sakmann and Erwin Neher. 2nd ed. New York: Plenum Press, c1995.ISBN 0-306-44870-X
  5. ^"Neher".Random House Webster's Unabridged Dictionary.
  6. ^"Nobel autobiography of Neher".
  7. ^"Neurotree - Erwin Neher Family Tree".neurotree.org.
  8. ^Dean, Chris."Erwin Neher - Science Video Interview".Vega Science Trust.
  9. ^"Erwin Neher – Biographical, The Nobel Prize in Physiology or Medicine 1991".nobelprize.org. Nobel Media AB. Retrieved15 December 2019.
  10. ^Schoenfeld 2006, p. 264.
  11. ^"Notable Signers".Humanism and Its Aspirations. American Humanist Association. Archived fromthe original on October 5, 2012. RetrievedOctober 4, 2012.
  12. ^"The Nobel Prize in Physiology or Medicine 1991".Nobelprize.org. Retrieved16 May 2011.
  13. ^Neher E, Sakmann B (March 1992). "The patch clamp technique".Scientific American.266 (3):44–51.Bibcode:1992SciAm.266c..44N.doi:10.1038/scientificamerican0392-44.PMID 1374932.
  14. ^Neher E (1992). "[6] Correction for liquid junction potentials in patch clamp experiments".Correction for liquid junction potentials in patch clamp experiments. Methods in Enzymology. Vol. 207. pp. 123–31.doi:10.1016/0076-6879(92)07008-C.ISBN 978-0-12-182108-1.PMID 1528115.
  15. ^Neher E (September 1988). "The use of the patch clamp technique to study second messenger-mediated cellular events".Neuroscience.26 (3):727–34.doi:10.1016/0306-4522(88)90094-2.PMID 2462183.S2CID 45756434.
  16. ^Neher E, Sakmann B, Steinbach JH (July 1978). "The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes".Pflügers Archiv.375 (2):219–28.doi:10.1007/BF00584247.PMID 567789.S2CID 8035857.
  17. ^ab"Erwin Neher Biographical".www.nobelprize.org. Retrieved10 March 2021.
  18. ^"Ralph W. Gerard Prize in Neuroscience".www.sfn.org. Retrieved2025-07-18.
  19. ^Deutsche Forschungsgemeinschaft."Liste der mit dem Gottfried Wilhelm Leibniz-Preis Ausgezeichneten"(PDF).www.dfg.de. Retrieved2025-07-18.
  20. ^"1990 - 1981 Awardees".Columbia University Irving Medical Center. 2022-11-11. Retrieved2025-07-18.
  21. ^"Honorary degrees awarded at Encaenia 2025 | University of Oxford".www.ox.ac.uk. 2025-06-25. Retrieved2025-07-03.

Further reading

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External links

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