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Ergocristine

From Wikipedia, the free encyclopedia
Chemical compound

Not to be confused withErgocryptine.
Pharmaceutical compound
Ergocristine
Legal status
Legal status
Identifiers
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.007.383Edit this at Wikidata
Chemical and physical data
FormulaC35H39N5O5
Molar mass609.727 g·mol−1
3D model (JSmol)
  • O=C3N1CCC[C@H]1[C@]2(O)O[C@](C(=O)N2[C@H]3Cc4ccccc4)(NC(=O)[C@@H]8/C=C7/c5cccc6c5c(c[nH]6)C[C@H]7N(C)C8)C(C)C
  • InChI=1S/C35H39N5O5/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34/h4-7,9-12,16,18,20,23,27-29,36,44H,8,13-15,17,19H2,1-3H3,(H,37,41)/t23-,27-,28+,29+,34-,35+/m1/s1 ☒N
  • Key:HEFIYUQVAZFDEE-MKTPKCENSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ergocristine is anergopeptine and one of theergotalkaloids.[1] As of February 24, 2010 ergocristine has been federally regulated. Because of the existingControlled Substances Act regulatory controls on theLSD precursorslysergic acid,lysergic acid amide,ergotamine, andergonovine,clandestine laboratory operators have sought uncontrolled sources of precursor material for the production of LSD. This has led to theillicit utilization of theprecursor chemical ergocristine as a direct substitute for ergotamine and ergonovine for the illicit production of LSD. In fact, the largest clandestine LSD laboratory ever,William Leonard Pickard andClyde Apperson, that was seized by theDrug Enforcement Administration (DEA) utilized ergocristine as the LSD precursor according to court documents.[2]

The DEA determined that ergocristine was readily available from commercial chemical suppliers. DEA had identified at least three suppliers of ergocristine, of which one distributor is located domestically; the other two are based inGermany and theCzech Republic.[3][2]

References

[edit]
  1. ^Stoll A (1952)."Recent investigations on ergot alkaloids".Fortschritte der Chemie Organischer Naturstoffe: 114–174 (159).ISBN 9783709171691.{{cite journal}}:ISBN / Date incompatibility (help)
  2. ^ab"Control of Ergocristine, a Chemical Precursor Used in the Illicit Manufacture of Lysergic Acid Diethylamide, as a List I Chemical"(PDF).Microgram Bulletin.43 (3): 24. 2010.
  3. ^"DEA Diversion Control Division". Archived fromthe original on 2013-12-26. Retrieved2013-12-25.
Ergolines
(incl.lysergines)
Clavines
(6,8-dimethylergolines)
Lysergamides
(lysergic acid amides)
Ergopeptines
(peptide ergolines)
Partial ergolines
Related compounds
Natural sources


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