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Elixir

From Wikipedia, the free encyclopedia
Sweet-flavored liquid used for medicinal purposes
For other uses, seeElixir (disambiguation).
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Label from a bottle of Elixir Raspail, claiming its effectiveness againstepidemic diseases

Anelixir is a sweet liquid used for medical purposes, to be taken orally and intended to cure one's illness.[1] When used as apharmaceutical preparation, an elixir contains at least oneactive ingredient designed to be taken orally.

Etymology

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The word was introduced in lateMiddle English, throughLatin from theArabicالإكسير (al-ʾiksīr), which in turn is theArabization of theAncient Greekξήριον (xērion)'powder for drying wounds' (fromξηρός (xēros)'dry').[1] For centuries,elixir primarily meant an ingredient used inalchemy, either referring to a liquid which purportedly converts lead to gold, or a substance or liquid which is believed to cure all ills andgive eternal life.

Types

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Non-medicated elixirs

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These are used assolvents or vehicles for the preparation of medicated elixirs. Active ingredients are dissolved in a 15–⁠50% by volume solution ofethyl alcohol:

Medicated elixirs

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These include:

East Asian vitamin drinks

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Daily non-alcoholic non-caffeinated 'vitamin drinks' have been popular in East Asia since the 1950s, withOronamin fromOtsuka Pharmaceutical perhaps the market leader. Packaged in brown light-proof bottles, these drinks have the reputation of being enjoyed by old men and other health-conscious individuals. Counterparts exist in South Korea and China.

Westernenergy drinks typically have caffeine and are targeted at a younger demographic, with colorful labels and printed claims of increased athletic/daily performance.

Pseudomedicinal drinks

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SeePatent medicine.

Composition

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Poster for Elixir Mondet, 1899

An elixir is ahydro-alcoholic solution of at least one active ingredient. The alcohol is mainly used to:

  • Solubilize the active ingredient(s) and some excipients
  • Retard the crystallization of sugar
  • Preserve the finished product
  • Provide a sharpness to the taste
  • Aid in masking the unpleasant taste of the active ingredient(s)
  • Enhance the flavor.

The lowest alcoholic quantity that will dissolve completely the active ingredient(s) and give a clear solution is generally chosen. High concentrations of alcohol give burning taste to the final product.

An elixir may also contain the followingexcipients:

Storage

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Elixirs should only be stored in a tightly closed, light resistant container away from direct heat and sunlight.

See also

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Look upelixir in Wiktionary, the free dictionary.

References

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  1. ^abChisholm, Hugh, ed. (1911)."Elixir" .Encyclopædia Britannica. Vol. 9 (11th ed.). Cambridge University Press. pp. 281–282.
Oral
Digestive tract (enteral)
Solids

Liquids
Oral mucosa (buccal,sublabial,sublingual)
Solids
Liquids
Respiratory tract (inhalation)
Solids
Liquids
Gas
Ophthalmic,
otic,nasal
Urogenital
Rectal (enteral)
Dermal (topical)
Skin (transdermal)
Organs
Central nervous system
Circulatory,
musculoskeletal
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