| Constituency | Date | Incumbent | Party | Winner | Party | Cause |
|---|
| Mid Armagh | 23 June 1921 | James Lonsdale | | UUP | Henry Armstrong | | UUP | Death |
| Belfast Duncairn | 23 June 1921 | Edward Carson | | UUP | Thomas McConnell | | UUP | AppointedLord of Appeal in Ordinary |
| North Down | 23 June 1921 | Thomas Watters Brown | | UUP | Thomas Watters Brown | | UUP | AppointedSolicitor-General for Ireland |
| Mid Down | 2 July 1921 | James Craig | | UUP | Robert Sharman-Crawford | | UUP | ElectedPrime Minister of Northern Ireland |
| West Down | 5 July 1921 | Daniel Martin Wilson | | UUP | Thomas Browne Wallace | | UUP | AppointedRecorder of Belfast |
| South Londonderry | 29 August 1921 | Denis Henry | | UUP | Robert Chichester | | UUP | AppointedLord Chief Justice of Northern Ireland |
| South Londonderry | 18 January 1922 | Robert Chichester | | UUP | William Pain | | UUP | Death |
| West Down | 17 February 1922 | Thomas Browne Wallace | | UUP | Hugh Hayes | | UUP | Appointed Chief Clerk to theHigh Court of Northern Ireland |
| North Down | 21 February 1922 | Thomas Watters Brown | | UUP | Sir Henry Wilson, Bt | | UUP | Appointed to theHigh Court of Northern Ireland |
| North Londonderry | 4 June 1922 | Hugh T. Barrie | | UUP | Malcolm Macnaghten | | UUP | Death |
| North Down | 21 July 1922 | Sir Henry Wilson, Bt | | UUP | John Simms | | UUP | Killed by theIRA |
| Londonderry | 29 January 1929 | Malcolm Macnaghten | | UUP | Ronald Ross | | UUP | Appointment toHigh Court of Justice of England and Wales |
| Fermanagh and Tyrone | 7 March 1931 | Thomas Harbison | | Nationalist | Cahir Healy | | Nationalist | Death |
| Fermanagh and Tyrone | 27 June 1934 | Joseph Devlin | | Nationalist | Joe Stewart | | Nationalist | Death |
| Down | 10 May 1939 | David Reid | | UUP | James Little | | UUP | Death |
| Belfast East | 8 February 1940 | Herbert Dixon | | UUP | Henry Harland | | UUP | Elevation to the Peerage |
| Queen's University of Belfast | 2 November 1940 | Thomas Sinclair | | UUP | Douglas Savory | | UUP | Resignation |
| Belfast West | 9 February 1943 | Alexander Browne | | UUP | Jack Beattie | | NI Labour | Death |
| Antrim | 11 February 1943 | Sir Joseph McConnell, Bt | | UUP | John Dermot Campbell | | UUP | Death |
| Down | 2 June 1946 | James Little | | Ind. Unionist | C. H. Mullan | | UUP | Death |
| Armagh | 5 March 1948 | Sir William Allen | | UUP | James Harden | | UUP | Death by road accident |
| Belfast West | 29 November 1950 | J. G. MacManaway | | UUP | Thomas Teevan | | UUP | Disqualified under theHouse of Commons (Clergy Disqualification) Act 1801 |
| Londonderry | 19 May 1951 | Ronald Ross | | UUP | William Wellwood | | UUP | Appointment as Northern Ireland Government Agent in London |
| North Antrim | 27 October 1952 | Sir Hugh O'Neill | | UUP | Phelim O'Neill | | UUP | Resignation |
| Belfast South | 4 November 1952 | Conolly Gage | | UUP | David Campbell | | UUP | Resignation |
| North Down | 15 April 1953 | Walter Smiles | | UUP | Patricia Ford | | UUP | Died inMVPrincess Victoria ferry disaster |
| Armagh | 20 November 1954 | James Harden | | UUP | C. W. Armstrong | | UUP | Resignation |
| Mid Ulster | 11 August 1955 | Tom Mitchell | | Sinn Féin | Tom Mitchell | | Sinn Féin | Disqualification |
| Mid Ulster | 8 May 1956 | Charles Beattie | | UUP | George Forrest | | Ind. Unionist | Disqualification |
| Belfast East | 19 March 1959 | Alan McKibbin | | UUP | Stanley McMaster | | UUP | Death |
| Belfast South | 22 October 1963 | Sir David Campbell | | UUP | Rafton Pounder | | UUP | Death |
| Mid Ulster | 17 April 1969 | George Forrest | | UUP | Bernadette Devlin | | Unity | Death |
| Fermanagh and South Tyrone | 9 April 1981 | Frank Maguire | | Ind. Nationalist | Bobby Sands | | Anti H-Block | Death |
| Fermanagh and South Tyrone | 20 August 1981 | Bobby Sands | | Anti H-Block | Owen Carron | | Anti H-Block | Death from hunger strike |
| Belfast South | 4 March 1982 | Robert Bradford | | UUP | Martin Smyth | | UUP | Killed by theIRA |
| Antrim North | 23 January 1986 | Ian Paisley | | DUP | Ian Paisley | | DUP | Resignation in protest atAnglo-Irish Agreement |
| Antrim East | 23 January 1986 | Roy Beggs | | UUP | Roy Beggs | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Antrim South | 23 January 1986 | Clifford Forsythe | | UUP | Clifford Forsythe | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Belfast East | 23 January 1986 | Peter Robinson | | DUP | Peter Robinson | | DUP | Resignation in protest at Anglo-Irish Agreement |
| Belfast North | 23 January 1986 | Cecil Walker | | UUP | Cecil Walker | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Belfast South | 23 January 1986 | Martin Smyth | | UUP | Martin Smyth | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Down North | 23 January 1986 | James Kilfedder | | UPUP | James Kilfedder | | UPUP | Resignation in protest at Anglo-Irish Agreement |
| Down South | 23 January 1986 | Enoch Powell | | UUP | Enoch Powell | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Fermanagh and South Tyrone | 23 January 1986 | Ken Maginnis | | UUP | Ken Maginnis | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Lagan Valley | 23 January 1986 | James Molyneaux | | UUP | James Molyneaux | | UUP | Resignation in protest at Anglo-Irish Agreement |
| East Londonderry | 23 January 1986 | William Ross | | UUP | William Ross | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Mid Ulster | 23 January 1986 | William McCrea | | DUP | William McCrea | | DUP | Resignation in protest at Anglo-Irish Agreement |
| Strangford | 23 January 1986 | John Taylor | | UUP | John Taylor | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Newry and Armagh | 23 January 1986 | James Nicholson | | UUP | Seamus Mallon | | SDLP | Resignation in protest at Anglo-Irish Agreement |
| Upper Bann | 23 January 1986 | Harold McCusker | | UUP | Harold McCusker | | UUP | Resignation in protest at Anglo-Irish Agreement |
| Upper Bann | 17 May 1990 | Harold McCusker | | UUP | David Trimble | | UUP | Death |
| North Down | 15 June 1995 | Sir James Kilfedder | | UPUP | Robert McCartney | | UK Unionist | Death |
| South Antrim | 21 September 2000 | Clifford Forsythe | | UUP | William McCrea | | DUP | Death |
| Belfast West | 9 June 2011 | Gerry Adams | | Sinn Féin | Paul Maskey | | Sinn Féin | Resignation to contest theLouth constituency in theIrish general election |
| Mid Ulster | 7 March 2013 | Martin McGuinness | | Sinn Féin | Francie Molloy | | Sinn Féin | Resignation to end dual mandate as Member of Parliament and Member of the Northern Ireland Assembly |
| West Tyrone | 3 May 2018 | Barry McElduff | | Sinn Féin | Órfhlaith Begley | | Sinn Féin | Resignation |