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ELF4

From Wikipedia, the free encyclopedia
Protein-coding gene in humans
ELF4
Identifiers
AliasesELF4, ELFR, MEF, E74 like ETS transcription factor 4, AIFBL2
External IDsOMIM:300775;MGI:1928377;HomoloGene:31036;GeneCards:ELF4;OMA:ELF4 - orthologs
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for ELF4
Genomic location for ELF4
BandXq26.1Start130,063,955bp[1]
End130,110,716bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for ELF4
Genomic location for ELF4
BandX|X A5Start47,499,923bp[2]
End47,552,009bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • granulocyte

  • blood

  • mononuclear cell

  • monocyte

  • cartilage tissue

  • germinal epithelium

  • mucosa of transverse colon

  • mucosa of ileum

  • jejunal mucosa

  • mucosa of sigmoid colon
Top expressed in
  • granulocyte

  • ascending aorta

  • aortic valve

  • urethra

  • male urethra

  • tibiofemoral joint

  • thymus

  • genital tubercle

  • lip

  • tail of embryo
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

2000

56501

Ensembl

ENSG00000102034

ENSMUSG00000031103

UniProt

Q99607

Q9Z2U4

RefSeq (mRNA)

NM_001127197
NM_001421

NM_019680
NM_001381876

RefSeq (protein)

NP_001120669
NP_001412

NP_062654
NP_001368805

Location (UCSC)Chr X: 130.06 – 130.11 MbChr X: 47.5 – 47.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ETS-related transcription factor Elf-4 is aprotein that in humans is encoded by theELF4gene.[5][6]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000102034Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000031103Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Miyazaki Y, Sun X, Uchida H, Zhang J, Nimer S (October 1996). "MEF, a novel transcription factor with an Elf-1 like DNA binding domain but distinct transcriptional activating properties".Oncogene.13 (8):1721–9.PMID 8895518.
  6. ^"Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)".

Further reading

[edit]

External links

[edit]
(1) Basic domains
(1.1) Basicleucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3)bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2)Zinc finger DNA-binding domains
(2.1)Nuclear receptor(Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3.1)Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3)Fork head /winged helix
(3.4)Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4)β-Scaffold factors with minor groove contacts
(4.1)Rel homology region
(4.2)STAT
(4.3) p53-like
(4.4)MADS box
(4.6)TATA-binding proteins
(4.7)High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3)Pocket domain
(0.5)AP-2/EREBP-related factors
(0.6) Miscellaneous


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