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EIF3J

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
EIF3J
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

2KRB,3BPJ

Identifiers
AliasesEIF3J, EIF3S1, eIF3-alpha, eIF3-p35, eukaryotic translation initiation factor 3 subunit J
External IDsOMIM:603910;MGI:3704486;HomoloGene:37845;GeneCards:EIF3J;OMA:EIF3J - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for EIF3J
Genomic location for EIF3J
Band15q21.1Start44,537,125bp[1]
End44,563,029bp[1]
Gene location (Mouse)
Chromosome 18 (mouse)
Chr.Chromosome 18 (mouse)[2]
Chromosome 18 (mouse)
Genomic location for EIF3J
Genomic location for EIF3J
Band18|18 B3Start43,608,483bp[2]
End43,610,861bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gastrocnemius muscle

  • biceps brachii

  • body of pancreas

  • muscle of thigh

  • sural nerve

  • epithelium of colon

  • Skeletal muscle tissue of rectus abdominis

  • Skeletal muscle tissue of biceps brachii

  • ganglionic eminence

  • gonad
Top expressed in
  • muscle of thigh

  • quadriceps femoris muscle

  • epiblast

  • tail of embryo

  • yolk sac

  • skeletal muscle tissue

  • placenta

  • embryo

  • embryo

  • zygote
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8669

100042807

Ensembl

ENSG00000104131

ENSMUSG00000043424

UniProt

O75822

Q66JS6

RefSeq (mRNA)

NM_003758
NM_001284335
NM_001284336

NM_001256055

RefSeq (protein)

NP_001271264
NP_001271265
NP_003749

NP_001242984

Location (UCSC)Chr 15: 44.54 – 44.56 MbChr 18: 43.61 – 43.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 3 subunit J (eIF3j) is aprotein that in humans is encoded by theEIF3Jgene.[5][6]

Interactions

[edit]

eIF3j has been shown tointeract witheIF3a.[5][7]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000104131 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000043424 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^abBlock KL, Vornlocher HP, Hershey JW (Dec 1998)."Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3".J. Biol. Chem.273 (48):31901–8.doi:10.1074/jbc.273.48.31901.PMID 9822659.
  6. ^"Entrez Gene: EIF3S1 eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa".
  7. ^Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003)."Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3".Eur. J. Biochem.270 (20):4133–9.doi:10.1046/j.1432-1033.2003.03807.x.PMID 14519125.

Further reading

[edit]

External links

[edit]
  • Overview of all the structural information available in thePDB forUniProt:O75822 (Human Eukaryotic translation initiation factor 3 subunit J (EIF3J)) at thePDBe-KB.
Proteins
Initiation factor
Bacterial
Mitochondrial
Archaeal
Eukaryotic
eIF1
eIF2
eIF3
eIF4
eIF5
eIF6
Elongation factor
Bacterial/Mitochondrial
Archaeal/Eukaryotic
Release factor
Ribosomal Proteins
Cytoplasmic
60S subunit
40S subunit
Mitochondrial
39S subunit
28S subunit
Other concepts


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