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EARS-Net

From Wikipedia, the free encyclopedia
Biological database
European Antimicrobial Resistance Surveillance Network (EARS-Net)
Content
DescriptionDatabase focused on documentation of eight bacterial pathogens in the EU.
Data types
captured
Antimicrobial resistance
OrganismsBacteria
Access
Websitewww.ecdc.europa.eu/en/about-us/partnerships-and-networks/disease-and-laboratory-networks/ears-net
Miscellaneous
Bookmarkable
entities
yes

EARS-Net otherwise known asEuropeanAntimicrobialResistanceSurveillanceNetwork is a central and comprehensivedatabase for theEuropean Union that focuses on eight differentbacterial pathogens.[1]

Scope

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EARS-Net tracks resistance rates reported in routine clinical antimicrobial susceptibility data from local and clinical laboratories, gathered by national surveillance programs and laboratory networks. Resistance status is determined according toEUCAST guidelines. Only data from invasive isolates (blood and cerebrospinal fluid) are included in EARS-Net.[2] The antibiotics for which resistance is tracked varies by species, and is based onEUCAST recommendations. Resistance data is collected for these eight pathogens only:[citation needed]

  • Escherichia coli
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa
  • Acinetobacter species
  • Streptococcus pneumoniae
  • Staphylococcus aureus
  • Enterococcus faecalis
  • Enterococcus faecium

Caveats

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Several factors can affect the reliability of inter-country comparisons of resistance rates, due to differences in data quality and biased introduced during data collection and reporting. Several identified by EARS-Net[2] are:

  • Population coverage: some countries have large surveillance networks that cover most of their population, while others use a smaller subset of hospitals and laboratories to generate data intended to be representative of the broader population.
  • Sampling: EARS-Net data are only collected for invasive isolates (from blood or cerebrospinal fluid). These samples may not be representative of the members of this species that can colonize and infect humans, so resistance rates for other infections, such as urinary tract infections may vary. In some settings, laboratory microbiology work may only be performed in cases where initial antibiotic treatment has failed, leading to an overestimation of resistance rates.
  • Laboratory routines and capacity: interpretation ofminimum inhibitory concentration may vary across laboratories and countries, depending on current practice. Recommendations around convertingminimum inhibitory concentration to resistance status also change over time,[3] making comparison of resistance rates over time challenging.

History

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EARS-Net is the collaborative effort of 29 countries. The information documented areantibiotic resistance which are determined according to theEUCAST standard.[1] Around 80% of the participants utilize the EUCAST standard for detection of antibiotic resistance.[1] EARS-Net was established in 1998 as EARSS, funded by the European Commission's Directorate General for Health and Consumer Affairs and the Dutch Ministry of Health, Welfare and Sports.[1] However, in January 2010, it was transferred to theEuropean Centre for Disease Prevention and Control (ECDC) where it was renamed EARS-Net.[1]

See also

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References

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  1. ^abcde"European Antimicrobial Resistance Surveillance Network (EARS-Net)".European Centre for Disease Prevention and Control. 19 May 2017. Retrieved2019-07-16.
  2. ^ab"Data collection and analysis".European Centre for Disease Prevention and Control. 19 May 2017. Retrieved12 December 2021.
  3. ^"EUCAST: Clinical breakpoints and dosing of antibiotics".www.eucast.org. Retrieved12 December 2021.
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