| Names | |
|---|---|
| IUPAC name 2-methyl-1-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine | |
| Other names (RS)-1-methyl-2-nitro-3-[(tetrahydro-3-furanyl) methyl] guanidine; MTI-446 | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChemSpider |
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| ECHA InfoCard | 100.111.831 |
| KEGG |
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| UNII | |
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| Properties[1] | |
| C7H14N4O3 | |
| Molar mass | 202.214 g·mol−1 |
| Melting point | 107.5 |
| 39.83 g/L | |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | ≥2000 mg/kg (oral, rat and mouse)[1] |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Dinotefuran is an insecticide of theneonicotinoid class developed byMitsui Chemicals for control of insect pests such asaphids,whiteflies,thrips,leafhoppers,leafminers,sawflies,mole cricket,white grubs,lacebugs,billbugs,beetles,mealybugs, andcockroaches on leafy vegetables, in residential and commercial buildings, and for professional turf management.[2] Itsmechanism of action involves disruption of the insect's nervous system byinhibitingnicotinic acetylcholine receptors.
In July 2013, the US state of Oregon temporarily restricted the use of dinotefuran pending the results of an investigation into a large bee kill.[3]
Dinotefuran is also used inveterinary medicine as aflea andtick preventive for dogs and as a flea preventive for cats. It is used in combination withpyriproxifen and/orpermethrin.[4][5]
Studies show dinotefuran is effective at controlling the invasivespotted lanternfly, first found in Berks County, PA, in 2014.[6]