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Dimetridazole

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Dimetridazole
Clinical data
AHFS/Drugs.comInternational Drug Names
ATCvet code
Identifiers
  • 1,2-dimethyl-5-nitro-1H-imidazole
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.008.184Edit this at Wikidata
Chemical and physical data
FormulaC5H7N3O2
Molar mass141.130 g·mol−1
3D model (JSmol)
  • Cc1ncc([N](=O)=O)n1C
  • InChI=1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3 checkY
  • Key:IBXPYPUJPLLOIN-UHFFFAOYSA-N checkY
  (verify)

Dimetridazole is a drug that combatsprotozoan infections. It is anitroimidazole class drug.[1] It used to be commonly added to poultry feed. This led to it being found in eggs. Because of suspicions of it being carcinogenic its use has been legally limited but it is still found in the eggs.[2][3] It is now banned as alivestock feed additive in many jurisdictions, for example in theEuropean Union,[4]Canada.[5] and theUnited States.[6] In the US, theFood and Drug Administration bans it forextralabel use[7]

See also

[edit]

References

[edit]
  1. ^Dalton, P. (1996). "Use of dimetridazole in gamebirds".The Veterinary Record.139 (16): 399.PMID 8913016.
  2. ^Posyniak A, Semeniuk S, Zmudzki J, Niedzielska J, Biernacki B (1996). "Residues of dimetridazole in eggs after treatment of laying hens".Veterinary Research Communications.20 (2):167–74.doi:10.1007/bf00385638.PMID 8711897.S2CID 38729121.
  3. ^Cannavan A, Kennedy DG (1997). "Determination of dimetridazole in poultry tissues and eggs using liquid chromatography-thermospray mass spectrometry".The Analyst.122 (9):963–6.Bibcode:1997Ana...122..963C.doi:10.1039/a703193i.PMID 9374025.
  4. ^Council Regulation (EEC) No 2377/90 of 26 June 1990[1]
  5. ^Canadian Food Inspection Agency updateArchived May 7, 2005, at theWayback Machine
  6. ^US Food and Drugs Administration, Food Additives Status List[2]
  7. ^US Food and Drug Administration, Code of Federal Regulations, Title 21, Volume 6, Revised as of April 1, 2020[3]


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