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| Trade names | Dovida, Pressamina, Superten |
| Other names | Dimethophrine; Dimetrophine; Dimethofrine; DMP; SM-14; 3,5-Dimethoxy-4,β-dihydroxy-N-methylphenethylamine; 3,5-Dimethoxy-4,β-dihydroxy-N-methyl-β-phenylethylamine |
| Routes of administration | Oral[1] |
| Drug class | α1-Adrenergic receptoragonist;Antihypotensive agent;Vasopressor |
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| ECHA InfoCard | 100.041.210 |
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| Formula | C11H17NO4 |
| Molar mass | 227.260 g·mol−1 |
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Dimetofrine (INNTooltip International Nonproprietary Name), also known asdimethophrine ordimetophrine and sold under the brand namesDovida,Pressamina, andSuperten, is amedication described as asympathomimetic,vasoconstrictor, andcardiac stimulant.[2][3][4] It is said to be similarly or less effective thanmidodrine in the treatment oforthostatic hypotension and shows substantially lowerpotency.[5][1]
The drug is aselectiveα1-adrenergic receptoragonist[6] but is also said to haveβ-adrenergic receptor agonist activity.[1] It is asubstituted phenethylamine and is also known as 3,5-dimethoxy-4,β-dihydroxy-N-methylphenethylamine.[2] Itschemical structure is similar to that ofdesglymidodrine (3,6-dimethoxy-β-hydroxyphenethylamine), theactive metabolite of midodrine.[5]
Dimetofrine remained marketed only inItaly in 2000.[3]
 | Thisdrug article relating to thecardiovascular system is astub. You can help Wikipedia byadding missing information. |
