 | |
| Clinical data | |
|---|---|
| Trade names | Fenistil |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral, topical |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChemCID | |
| DrugBank |
|
| ChemSpider |
|
| UNII | |
| KEGG |
|
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.024.622 |
| Chemical and physical data | |
| Formula | C20H24N2 |
| Molar mass | 292.426 g·mol−1 |
| 3D model (JSmol) | |
| Chirality | Racemic mixture |
| |
| |
| (verify) | |
Dimetindene, also sold under the brand nameFenistil, is anantihistamine/anticholinergic. It is a first generation[1] selectiveH1 antagonist.[2] Dimetindene is an atypical first generation H1 antagonist as it only minimally[3] passes across theblood–brain barrier.
Dimetindene is also anM2 receptor antagonist.[4]
It was patented in 1958 and came into medical use in 1960.[5]
Dimetindene is used orally and topically as anantipruritic.[6] It is used topically to treat skin irritations, such as insect bites. Dimetindene is also administered orally to treat allergies, such ashay fever.
It is commonlyformulated as itsmaleic acidsalt, dimethindene maleate.
It is sold under the brand nameFenistil among others.
