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| Names | |
|---|---|
| IUPAC name 21-Hydroxy-5α-pregnane-3,20-dione | |
| Systematic IUPAC name (1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
| Other names 5α-Dihydro-11-deoxycorticosterone | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChemSpider | |
| UNII | |
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| Properties | |
| C21H32O3 | |
| Molar mass | 332.484 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
5α-Dihydrodeoxycorticosterone (abbreviated asDHDOC), also known as21-hydroxy-5α-pregnan-20-one, is anendogenousprogestogen andneurosteroid.[1] It is synthesized from theadrenal hormonedeoxycorticosterone (DOC) by theenzyme5α-reductase type I.[1] DHDOC is anagonist of theprogesterone receptor, as well as apositive allosteric modulator of theGABAA receptor, and is known to haveanticonvulsant effects.[1][2]
