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Desoximetasone

From Wikipedia, the free encyclopedia
Chemical compound
"Esperson" redirects here; not to be confused withEpperson orEsperson Buildings.
Pharmaceutical compound
Desoximetasone
Clinical data
Trade namesTopicort, Emcor, Desacort
AHFS/Drugs.comMonograph
MedlinePlusa605026
Routes of
administration
Topical
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • (8S,9S,10S,11S,13S,14S,16R,17S)-9-Fluoro-11- hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 7,8,11,12,14,15,16,17-octahydro-6H- cyclopenta[a]phenanthren-3-one
CAS Number
PubChemCID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.006.224Edit this at Wikidata
Chemical and physical data
FormulaC22H29FO4
Molar mass376.468 g·mol−1
3D model (JSmol)
  • OCC(=O)[C@H]3[C@H](C)CC2C4CC/C1=C/C(=O)\C=C/[C@]1(C)[C@@]4(F)[C@@H](O)C[C@@]23C
  • InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15?,16?,18+,19-,20+,21+,22+/m1/s1 checkY
  • Key:VWVSBHGCDBMOOT-ZIKVJHDZSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Desoximetasone is a medication belonging to the family of medications known as topicalcorticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation.[1] Desoximetasone is a synthetic corticosteroid, a class of primarily synthetic steroids used asanti-inflammatory andanti-pruritic agents.

Three brand name products are available (availability depending on country):

  • Topicort Emollient Cream (0.25% desoximetasone)
  • Topicort LP Emollient Cream (0.05% desoximetasone)
  • Topisolone Cream (0.25% desoximetasone)

Usage

[edit]

When using desoximetasone, some of the medication may be absorbed through the skin and into the bloodstream. Too much absorption can lead to unwanted side effects elsewhere in the body. Large amounts of desoximetasone should be avoided over large areas. It should not be used for extended periods of time. Treated areas should not be covered with airtight dressings such as plastic wrap or adhesive bandages.[1] Children may absorb more medication than adults do. Desoximetasone is for use only on the skin and should be kept out of the eyes.

Desoximetasone can also be used to treat some types ofpsoriasis.

See also

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References

[edit]
  1. ^ab"Desoximetasone Topical".Medline Plus. U.S. National Library of Medicine.

External links

[edit]
Glucocorticoids
Natural
Synthetic
Antiglucocorticoids
Synthesis modifiers
GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
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