| Desmoplastic fibroma | |
|---|---|
| Specialty | Oncology |
Inmedicine, adesmoplastic fibroma is alow-grademalignant, locally aggressive, fibrous and rare tumor of the bone, affecting children and young adults, potentially resulting incortical bone destruction. It usually affects craniofacial bones, mandible most frequently, long bones (metaphyseal femur, tibia, humerus).[1] The World Health Organization, 2020, reclassified these tumors as specific benign tumors in the category offibroblastic and myofibroblastic tumors.[2]
Although it does not tend tometastatize, it has a high localrecurrence and infiltrative growth.[3] Treatment consists in wide local excision to prevent otherwise frequent recurrences.[4] The role ofradiotherapy andchemotherapy in this tumor still is unclear.[5]
Some cases have been described, in which anosteosarcoma has arisen from a desmoplastic fibroma.[6]
A famous occurrence of this particular form of the disease involved Italo-AustralianRiccardo Torresan in 2011, with 18 cm of femur needing to be removed with the now widely recognized method of "aggressive curettage" being employed.[7]
